Clinical and Histopathological Features of Irritant Contact Dermatitis in Dogs

Aim: The aim of this study was to investigate the incidence, clinical presentation, and histopathological characteristics of irritant contact dermatitis in dogs, with a focus on irritant-induced cases, and to identify common causative agents. Study Design: A cross-sectional observational study was conducted over a six-month period from February to July 2024 at the dermatology unit of Madras Veterinary College, Chennai. Methodology: Out of 4,972 dogs presented to the outpatient unit during the study period, dogs suspected to have contact dermatitis were selected. Detailed history, clinical examination, hematological and biochemical profiles, and histopathological evaluations were performed. Data on breed, age, coat type, exposure to potential irritants, and lesion distribution were recorded. Results: A total of 32 cases (0.64%) were diagnosed with irritant contact dermatitis. The condition was more prevalent in male dogs aged between 1–3 years and among medium-coated breeds. Common irritants included floor disinfectants (phenols, bleach), antiseptic solutions (chlorhexidine), shampoos, and fertilizers. Lesions primarily affected sparsely haired areas such as the abdomen, groin, paws, and axilla. Clinical signs included erythema, alopecia, scaling, and papulopustular eruptions. Hematological analysis showed stress leukograms; biochemistry revealed hypoalbuminemia and mild ALT elevation. Histopathology showed epidermal hyperplasia, parakeratosis, spongiosis, and dermal infiltration with mononuclear cells. Conclusion: Irritant contact dermatitis in dogs, presents with distinct clinical and histopathological features. A systematic approach involving exposure history, lesion distribution, and histopathology is essential for accurate diagnosis and effective management. Increased awareness among pet owners and veterinarians is key to prevention and early intervention

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Publication Details

Journal
Journal of Advances in Biology & Biotechnology
Published
2025-07-24
DOI
https://doi.org/10.9734/jabb/2025/v28i82678
Primary Topic
Dermatology and Skin Diseases
Type
article
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article

Clinical and Histopathological Features of Irritant Contact Dermatitis in Dogs

Shau-Chi Chi, G. H. Rao, G Vijayakumar, S Ramesh et al.
Journal of Advances in Biology & Biotechnology
Dermatology and Skin Diseases
article

Clinical and Histopathological Features of Irritant Contact Dermatitis in Dogs

Shau-Chi Chi, G. H. Rao, G Vijayakumar, S Ramesh, M. Sandhya Bhavani, Mani Bharathi M, G Navyasree
article en

Abstract

Aim: The aim of this study was to investigate the incidence, clinical presentation, and histopathological characteristics of irritant contact dermatitis in dogs, with a focus on irritant-induced cases, and to identify common causative agents. Study Design: A cross-sectional observational study was conducted over a six-month period from February to July 2024 at the dermatology unit of Madras Veterinary College, Chennai. Methodology: Out of 4,972 dogs presented to the outpatient unit during the study period, dogs suspected to have contact dermatitis were selected. Detailed history, clinical examination, hematological and biochemical profiles, and histopathological evaluations were performed. Data on breed, age, coat type, exposure to potential irritants, and lesion distribution were recorded. Results: A total of 32 cases (0.64%) were diagnosed with irritant contact dermatitis. The condition was more prevalent in male dogs aged between 1–3 years and among medium-coated breeds. Common irritants included floor disinfectants (phenols, bleach), antiseptic solutions (chlorhexidine), shampoos, and fertilizers. Lesions primarily affected sparsely haired areas such as the abdomen, groin, paws, and axilla. Clinical signs included erythema, alopecia, scaling, and papulopustular eruptions. Hematological analysis showed stress leukograms; biochemistry revealed hypoalbuminemia and mild ALT elevation. Histopathology showed epidermal hyperplasia, parakeratosis, spongiosis, and dermal infiltration with mononuclear cells. Conclusion: Irritant contact dermatitis in dogs, presents with distinct clinical and histopathological features. A systematic approach involving exposure history, lesion distribution, and histopathology is essential for accurate diagnosis and effective management. Increased awareness among pet owners and veterinarians is key to prevention and early intervention

Journal of Advances in Biology & BiotechnologyVol. 28(8)
Madras Medical College (IN), University of Madras (IN), Kerala Veterinary and Animal Sciences University (IN), Tamil Nadu Veterinary and Animal Sciences University (IN)
Openalex Percentile: Top 67%
Dermatology and Skin Diseases
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