Trifecta of Cysts: Unraveling the Diagnosis in a Patient With Renal, Hepatic, and Pancreatic Cysts

Multiorgan cysts, affecting multiple organs such as the liver, kidneys, and pancreas, pose a diagnostic and therapeutic challenge. The etiology is diverse, including congenital conditions, like polycystic kidney disease (PKD) and von Hippel-Lindau (VHL) syndrome, as well as secondary causes, like infection or neoplasms. The clinical presentation ranges from incidental findings to life-threatening complications. This case report discusses a 65-year-old female patient who presented with abdominal pain and was incidentally found to have hepatic, renal, and pancreatic cysts. Diagnostic workup, including computed tomography (CT), magnetic resonance imaging (MRI), and laboratory tests, ruled out primary genetic conditions, and management involved conservative monitoring and surgical interventions for bile leakage. The case emphasizes the complexity of diagnosing and managing multiorgan cysts and the importance of multidisciplinary care. The report highlights the need for further research to enhance diagnostic accuracy and improve therapeutic strategies in managing multiorgan cysts.