The potential mechanism of Saikosaponin D against luminal A breast cancer based on bioinformatical analysis, molecular docking and in vitro studies
SSD may have therapeutic potential in estrogen receptor-positive breast cancer, may through its suppression on ESR1.
Authors
- Ru Chang
- Jianzhen Pan
- Lichang Yang
- Shan Huang (ORCID: https://orcid.org/0000-0002-2269-1741)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Central South University (CN)
- Harbin Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Hunan Cancer Hospital (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Chongqing Medical and Pharmaceutical College (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1186/s41065-025-00510-8
- Citations
- 1
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 1.82