EphrinB2 alleviates tubulointerstitial fibrosis in diabetic kidney disease
EphrinB2 exerts protective effects against renal fibrosis and dysfunction in diabetic conditions by regulating fibrosis pathways, mitochondrial dynamics, and epithelial stability. Targeting EphrinB2 signaling presents a promising therapeutic strategy for diabetic kidney disease.
Authors
- Jinhu Chen (ORCID: https://orcid.org/0000-0002-4923-5076)
- Xiaoyan Wu (ORCID: https://orcid.org/0000-0002-3231-9775)
- Lihua Ni (ORCID: https://orcid.org/0000-0002-0456-3279)
- Xueyun Gao (ORCID: https://orcid.org/0000-0002-2267-9945)
- Yuan Cheng (ORCID: https://orcid.org/0000-0002-0226-614X)
- Feng Chen (ORCID: https://orcid.org/0000-0003-3508-8834)
- Qiuyuan Zhou
- Ayinigaer Yusufu
Institutions
- China Three Gorges University (CN)
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Yichang Central People's Hospital (CN)
- Hubei Cancer Hospital (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1186/s12967-025-06852-1
- Citations
- 2
- Primary Topic
- Ginkgo biloba and Cashew Applications
- Type
- article
- Field-Weighted Citation Impact
- 4.76
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Wuhan University
- Zhongnan Hospital of Wuhan University