A Multi-Modal Pelvic MRI Dataset for Deep Learning-Based Pelvic Organ Segmentation in Endometriosis

Endometriosis affects approximately 190 million females of reproductive age worldwide. Magnetic Resonance Imaging (MRI) has been recommended as the primary non-invasive diagnostic method for endometriosis. This study presents new female pelvic MRI multicenter datasets for endometriosis and shows the baseline segmentation performance of two auto-segmentation pipelines: the self-configuring nnU-Net and RAovSeg, a custom network. The multi-sequence endometriosis MRI scans from two clinical institutions were collected. A multicenter dataset of 51 subjects with manual labels for multiple pelvic structures from three raters was used to assess interrater agreement. A second single-center dataset of 81 subjects with labels for multiple pelvic structures from one rater was used to develop the ovary auto-segmentation pipelines. Uterus and ovary segmentations are available for all subjects, endometrioma segmentation is available for all subjects where it is detectable in the image. This study highlights the challenges of manual ovary segmentation in endometriosis MRI and emphasizes the need for an auto-segmentation method. The dataset is publicly available for further research in pelvic MRI auto-segmentation to support endometriosis research.

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Publication Details

Journal
Scientific Data
Published
2025-07-24
DOI
https://doi.org/10.1038/s41597-025-05623-3
Citations
1
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
1.70

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A Multi-Modal Pelvic MRI Dataset for Deep Learning-Based Pelvic Organ Segmentation in Endometriosis

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A Multi-Modal Pelvic MRI Dataset for Deep Learning-Based Pelvic Organ Segmentation in Endometriosis

Sunil A. Sheth, Xiaoming Guan, Varaha S. Tammisetti, Luca Giancardo, Xiaomin Liang, Kirk Roberts, Kamand Khalaj, Linda Alpuing Radilla, Haaniya Dawoodally, Chinmay Mokashi
article en
1 citations

Abstract

Endometriosis affects approximately 190 million females of reproductive age worldwide. Magnetic Resonance Imaging (MRI) has been recommended as the primary non-invasive diagnostic method for endometriosis. This study presents new female pelvic MRI multicenter datasets for endometriosis and shows the baseline segmentation performance of two auto-segmentation pipelines: the self-configuring nnU-Net and RAovSeg, a custom network. The multi-sequence endometriosis MRI scans from two clinical institutions were collected. A multicenter dataset of 51 subjects with manual labels for multiple pelvic structures from three raters was used to assess interrater agreement. A second single-center dataset of 81 subjects with labels for multiple pelvic structures from one rater was used to develop the ovary auto-segmentation pipelines. Uterus and ovary segmentations are available for all subjects, endometrioma segmentation is available for all subjects where it is detectable in the image. This study highlights the challenges of manual ovary segmentation in endometriosis MRI and emphasizes the need for an auto-segmentation method. The dataset is publicly available for further research in pelvic MRI auto-segmentation to support endometriosis research.

Scientific DataVol. 12(1)
Baylor College of Medicine (US), Texas Children's Hospital (US), The University of Texas Health Science Center (US), The University of Texas Health Science Center at Houston (US)
Robert and Janice McNair Foundation, Cancer Prevention and Research Institute of Texas, Texas Children's Hospital, National Institutes of Health
Openalex Percentile: Top 15%
Endometriosis Research and Treatment
1.70
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