CPAP improves regional lung strain rate and diaphragm velocity of relaxation in experimental self-inflicted lung injury
Standard oxygen therapy resulted in worse patterns of lung strain rate and diaphragm velocity of relaxation, consistent with P-SILI and load-induced diaphragm injury. CPAP resulted in improved lung function, decreased lung strain rate, and diaphragmatic relaxation velocity throughout the respiratory cycle. We conclude that CPAP promotes biomechanical protection in injured lungs and diaphragm, more noticeably during the expiratory phase.
Authors
- Sonia Reveco (ORCID: https://orcid.org/0000-0003-3236-1508)
- Pablo Cruces (ORCID: https://orcid.org/0000-0001-9337-1254)
- Benjamín Erranz
- A. Perez
- Daniel E. Hurtado (ORCID: https://orcid.org/0000-0001-6261-9106)
- Nibaldo Avilés-Rojas
- Carlos González (ORCID: https://orcid.org/0000-0002-7639-0434)
Institutions
- Pontificia Universidad Católica de Chile (CL)
- Universidad Andrés Bello (CL)
Publication Details
- Journal
- Critical Care
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1186/s13054-025-05536-y
- Citations
- 7
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 10.63
Funders
- Agencia Nacional de Investigación y Desarrollo