Association of novel triglyceride-glucose-related indices with incident stroke in early-stage cardiovascular-kidney-metabolic syndrome
Novel TyG-related indices, particularly TyG-CVAI, showed significant and incremental predictive value for stroke risk among individuals with CKM syndrome stages 0-3. Their incorporation into risk stratification frameworks may enhance early detection and prevention of cerebrovascular events in metabolically vulnerable populations.
Authors
- Rumi Murayama
- Kenji Hashimoto (ORCID: https://orcid.org/0000-0002-8892-0439)
- Zhengyu Sun (ORCID: https://orcid.org/0000-0002-2201-5700)
- Zongping Li (ORCID: https://orcid.org/0000-0002-6079-8339)
- Pengcheng Li (ORCID: https://orcid.org/0000-0002-1778-7095)
- Ye Zhang (ORCID: https://orcid.org/0000-0002-0229-9718)
- Yong Yue (ORCID: https://orcid.org/0000-0003-0282-5826)
Institutions
- Mianyang Central Hospital (CN)
- First Affiliated Hospital of Chengdu Medical College (CN)
- Center for Forensic Mental Health, Chiba University (JP)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1186/s12933-025-02854-x
- Citations
- 25
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 32.96