Low‐dose versus high‐dose methylprednisolone for children with severe <i>Mycoplasma pneumoniae</i> pneumonia (MCMP): A randomized controlled trial
Azithromycin combined with low-dose methylprednisolone demonstrates non-inferior efficacy in reducing pulmonary lesions at 6-month follow-up compared to combined with high-dose methylprednisolone while exhibiting a more favorable safety profile.
Authors
- Xiaoxia Peng (ORCID: https://orcid.org/0000-0001-8789-469X)
- Hao Wang (ORCID: https://orcid.org/0000-0001-9932-5339)
- Keqing Zhang (ORCID: https://orcid.org/0000-0003-2255-8454)
- Ruohua Yan (ORCID: https://orcid.org/0000-0003-1423-5962)
- Yiqin Song
- Nan Yang
- Yong Feng (ORCID: https://orcid.org/0000-0003-3940-1429)
- Boqun Xu (ORCID: https://orcid.org/0000-0001-7157-8078)
- Yunxiao Shang (ORCID: https://orcid.org/0000-0002-8885-4937)
- Jie Chang (ORCID: https://orcid.org/0000-0003-1814-8508)
- Anxia Jiao
- John S. Ji (ORCID: https://orcid.org/0000-0002-5002-118X)
- Liwei Gao (ORCID: https://orcid.org/0000-0001-7652-7456)
- Liping Liu (ORCID: https://orcid.org/0000-0001-7017-301X)
- Jun Liu (ORCID: https://orcid.org/0000-0002-1943-3880)
- Yao Yao (ORCID: https://orcid.org/0000-0002-5745-2310)
- Ning Chen (ORCID: https://orcid.org/0000-0002-8191-6744)
- Xiaojuan Zhang (ORCID: https://orcid.org/0000-0002-4441-0197)
- Ju Yin
- Ling Cao (ORCID: https://orcid.org/0000-0001-7139-0403)
- Xiaoning Wu (ORCID: https://orcid.org/0000-0001-7002-4305)
- Adong Shen (ORCID: https://orcid.org/0000-0001-9892-3361)
- Kunling Shen (ORCID: https://orcid.org/0009-0001-0045-6468)
- Xinyu Wang (ORCID: https://orcid.org/0000-0002-9602-698X)
- Bo Peng (ORCID: https://orcid.org/0000-0002-7774-4660)
- Zhiying Han
- Yan Yang
- He Zhang (ORCID: https://orcid.org/0000-0003-2959-4714)
Institutions
- Local Initiatives Support Corporation (US)
- Capital Medical University (CN)
- Vanke (China) (CN)
- Beijing Children’s Hospital (CN)
- Shanxi Provincial Children's Hospital (CN)
- China Medical University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Pediatric Investigation
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1002/ped4.70014
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Municipal Health Commission
- Chinese Academy of Medical Sciences
- Peking University