Low‐dose versus high‐dose methylprednisolone for children with severe <i>Mycoplasma pneumoniae</i> pneumonia (MCMP): A randomized controlled trial

Azithromycin combined with low-dose methylprednisolone demonstrates non-inferior efficacy in reducing pulmonary lesions at 6-month follow-up compared to combined with high-dose methylprednisolone while exhibiting a more favorable safety profile.

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Publication Details

Journal
Pediatric Investigation
Published
2025-07-24
DOI
https://doi.org/10.1002/ped4.70014
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00

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article

Low‐dose versus high‐dose methylprednisolone for children with severe Mycoplasma pneumoniae pneumonia (MCMP): A randomized controlled trial

Xiaoxia Peng, Hao Wang, Keqing Zhang, Ruohua Yan et al.
Pediatric Investigation
Pneumonia and Respiratory Infections
article

Low‐dose versus high‐dose methylprednisolone for children with severe Mycoplasma pneumoniae pneumonia (MCMP): A randomized controlled trial

Xiaoxia Peng, Hao Wang, Keqing Zhang, Ruohua Yan, Yiqin Song, Nan Yang, Yong Feng, Boqun Xu, Yunxiao Shang, Jie Chang, Anxia Jiao, John S. Ji, Liwei Gao, Liping Liu, Jun Liu, Yao Yao, Ning Chen, Xiaojuan Zhang, Ju Yin, Ling Cao, Xiaoning Wu, Adong Shen, Kunling Shen, Xinyu Wang, Bo Peng, Zhiying Han, Yan Yang, He Zhang
article en

Abstract

Azithromycin combined with low-dose methylprednisolone demonstrates non-inferior efficacy in reducing pulmonary lesions at 6-month follow-up compared to combined with high-dose methylprednisolone while exhibiting a more favorable safety profile.

Pediatric InvestigationVol. 9(3)
Local Initiatives Support Corporation (US), Capital Medical University (CN), Vanke (China) (CN), Beijing Children’s Hospital (CN), Shanxi Provincial Children's Hospital (CN), China Medical University (CN), Tsinghua University (CN)
Beijing Municipal Health Commission, Chinese Academy of Medical Sciences, Peking University
Openalex Percentile: Top 74%
Pneumonia and Respiratory Infections
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