Coronary Artery Disease–Based Polygenic Risk Score in Early-Onset Acute Myocardial Infarction Subtypes

PRS-CAD's association with AMI varied by subtype but not by sex in young adults, warranting caution in application.

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Publication Details

Journal
JACC Advances
Published
2025-07-24
DOI
https://doi.org/10.1016/j.jacadv.2025.101994
Citations
1
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
Field-Weighted Citation Impact
1.39

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article

Coronary Artery Disease–Based Polygenic Risk Score in Early-Onset Acute Myocardial Infarction Subtypes

Anthony Philippakis, Erica S. Spatz, David Herrington, Judith H. Lichtman et al.
1 citations
JACC Advances
Cardiovascular Function and Risk Factors
1.39
article

Coronary Artery Disease–Based Polygenic Risk Score in Early-Onset Acute Myocardial Infarction Subtypes

Anthony Philippakis, Erica S. Spatz, David Herrington, Judith H. Lichtman, Gail D’Onofrio, Amit V. Khera, Weilai Dong, Jerome I. Rotter, Wendy S. Post, Mitsuaki Sawano, Rachel P. Dreyer, Stephen S. Rich, César Caraballo, Yuntian Liu, Yuan Lu, Harlan M. Krumholz, Shu‐Xia Li
article en
1 citations

Abstract

PRS-CAD's association with AMI varied by subtype but not by sex in young adults, warranting caution in application.

JACC AdvancesVol. 4(8)
Broad Institute (US), Brigham and Women's Hospital (US), Yale New Haven Hospital (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), UCLA Medical Center (US), Yale University (US), Yale New Haven Health System (US), Harbor–UCLA Medical Center (US), Wake Forest University (US), University of Virginia (US)
National Heart, Lung, and Blood Institute
Good health and well-being
Openalex Percentile: Top 17%
Cardiovascular Function and Risk Factors
1.39
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Coronary Artery Disease–Based Polygenic Risk Score in Early-Onset Acute Myocardial Infarction Subtypes — Anthony Philippakis, Erica S. Spatz, et al. · JACC Advances (2025) | TGRS Research Map | TGRS