The relationship between α4β2-nicotinic acetylcholine receptor availability and brain arousal regulation as assessed by 2-[18F]F-A85380 PET and EEG following nicotine cessation in male individuals with nicotine dependence
The findings may suggest that the brain arousal regulation in some of the male participants may become more instable following a 7-day smoking cessation despite increased α4β2-nAChR binding. However, this sample limits the generalizability, and further studies with larger cohorts are needed.
Authors
- Osama Sabri (ORCID: https://orcid.org/0000-0002-6425-3504)
- Michael Rullmann (ORCID: https://orcid.org/0000-0002-2683-9432)
- Israel Guerrero
- Nicole Mauche (ORCID: https://orcid.org/0000-0002-4223-5030)
- Georg Becker (ORCID: https://orcid.org/0000-0002-9316-9125)
- Jue Huang (ORCID: https://orcid.org/0000-0003-1830-9340)
- Bernhard Sattler (ORCID: https://orcid.org/0000-0003-3862-2609)
- Ulrich Hegerl (ORCID: https://orcid.org/0000-0002-3039-7470)
- Maria Strauß (ORCID: https://orcid.org/0000-0002-0072-2199)
- Franziska Zientek (ORCID: https://orcid.org/0000-0002-0580-8872)
- Swen Hesse (ORCID: https://orcid.org/0000-0002-2055-2764)
- Philipp Meyer (ORCID: https://orcid.org/0000-0002-4692-9320)
Institutions
- Goethe University Frankfurt (DE)
- IPPMed (Germany) (DE)
- St. Josefs-Hospital Cloppenburg (DE)
- University Hospital Frankfurt (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Psychiatry Research Neuroimaging
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1016/j.pscychresns.2025.112035
- Citations
- 1
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 0.81