Interaction of metabolic and inflammatory dysregulation on central degeneration and cognitive function in behavioral variant Frontotemporal dementia
This study shows that bvFTD exhibits peripheral metabolic and inflammatory dysregulation, which are associated with frontotemporal lobar degeneration and clinical symptoms, and the interaction effects of metabolic and inflammatory dysregulation have a greater impact on bvFTD.
Authors
- Deming Jiang (ORCID: https://orcid.org/0000-0002-8835-5812)
- Min Kyung Chu (ORCID: https://orcid.org/0000-0001-6221-1346)
- Liyong Wu (ORCID: https://orcid.org/0000-0002-1251-6130)
- Qianqian He (ORCID: https://orcid.org/0000-0001-7559-9183)
- Zhongyun Chen (ORCID: https://orcid.org/0000-0001-6708-8391)
- Ailing Yue
- Miao Qu (ORCID: https://orcid.org/0000-0001-6289-9654)
- Yang Xu (ORCID: https://orcid.org/0000-0002-4460-8013)
- Yufei Chen (ORCID: https://orcid.org/0000-0002-5782-3556)
- Hua Rong Lu (ORCID: https://orcid.org/0000-0002-5211-1410)
- Jia‐Hui Hou
Institutions
- Capital Medical University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1007/s00415-025-13268-w
- Citations
- 3
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.53
Funders
- National Natural Science Foundation of China