Shared blood gene signature in lung adenocarcinoma and microbial lung infections: a bioinformatic analysis and in silico validation
This analysis identified a blood-based 7-gene signature shared between LUAD and microbial lung infections, associated with immunosuppressive microenvironment features, suggesting a potential link between infection-driven inflammation and tumor-promoting immune modulation.
Authors
- Masoud Arabfard (ORCID: https://orcid.org/0000-0003-3955-613X)
- Mostafa Ghanei (ORCID: https://orcid.org/0000-0003-2121-4764)
- Milad Sheervalilou
Institutions
- Baqiyatallah University of Medical Sciences (IR)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1007/s12672-025-03272-x
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Baqiyatallah University of Medical Sciences