Atypical Carcinoid of the Thymus: Early Diagnosis in a Case Report

<b>Background</b>: Atypical carcinoid of the thymus is an exceptionally rare neuroendocrine tumor originating from neuroendocrine cells within the thymus. These tumors often present with no symptoms or with nonspecific clinical signs, making early diagnosis particularly challenging. Despite their rarity, atypical carcinoids are clinically significant due to their aggressive nature and relatively poor prognosis. Early detection and appropriate management are therefore crucial to improving patient outcomes. <b>Results</b>: In this report, we present the case of a 64-year-old patient in whom an atypical carcinoid of the thymus was incidentally discovered following a thoracic computed tomography scan performed for unrelated reasons. Imaging revealed a suspicious anterior mediastinal mass, which was subsequently surgically resected. Histopathological examination, supported by immunohistochemical analysis, confirmed the diagnosis of an atypical carcinoid of the thymus. The tumor demonstrated coexpression of epithelial and neuroendocrine markers, consistent with this rare entity. <b>Conclusions</b>: This case adds to the limited body of literature on atypical carcinoid of the thymus and highlights the importance of considering this diagnosis when evaluating anterior mediastinal masses. It also underscores the value of thorough radiological and pathological assessment in identifying early-stage disease, which may significantly influence prognosis and therapeutic strategies.

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Journal
Medical Sciences
Published
2025-07-24
DOI
https://doi.org/10.3390/medsci13030096
Primary Topic
Myasthenia Gravis and Thymoma
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article
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article

Atypical Carcinoid of the Thymus: Early Diagnosis in a Case Report

Antonio Mier-Briseño, Miguel Armando Benavides-Huerto, Francisco Alejandro Lagunas‐Rangel, Ismael Padilla-Ponce
Medical Sciences
Myasthenia Gravis and Thymoma
article

Atypical Carcinoid of the Thymus: Early Diagnosis in a Case Report

Antonio Mier-Briseño, Miguel Armando Benavides-Huerto, Francisco Alejandro Lagunas‐Rangel, Ismael Padilla-Ponce
article en

Abstract

<b>Background</b>: Atypical carcinoid of the thymus is an exceptionally rare neuroendocrine tumor originating from neuroendocrine cells within the thymus. These tumors often present with no symptoms or with nonspecific clinical signs, making early diagnosis particularly challenging. Despite their rarity, atypical carcinoids are clinically significant due to their aggressive nature and relatively poor prognosis. Early detection and appropriate management are therefore crucial to improving patient outcomes. <b>Results</b>: In this report, we present the case of a 64-year-old patient in whom an atypical carcinoid of the thymus was incidentally discovered following a thoracic computed tomography scan performed for unrelated reasons. Imaging revealed a suspicious anterior mediastinal mass, which was subsequently surgically resected. Histopathological examination, supported by immunohistochemical analysis, confirmed the diagnosis of an atypical carcinoid of the thymus. The tumor demonstrated coexpression of epithelial and neuroendocrine markers, consistent with this rare entity. <b>Conclusions</b>: This case adds to the limited body of literature on atypical carcinoid of the thymus and highlights the importance of considering this diagnosis when evaluating anterior mediastinal masses. It also underscores the value of thorough radiological and pathological assessment in identifying early-stage disease, which may significantly influence prognosis and therapeutic strategies.

Medical SciencesVol. 13(3)
Uppsala University (SE), Universidad de Morelia (MX), Instituto Politécnico Nacional (MX), Instituto Tecnológico de Morelia (MX), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
Openalex Percentile: Top 72%
Myasthenia Gravis and Thymoma
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Atypical Carcinoid of the Thymus: Early Diagnosis in a Case Report — Antonio Mier-Briseño, Miguel Armando Benavides-Huerto, et al. · Medical Sciences (2025) | TGRS Research Map | TGRS