Meclizine Use and Subsequent Falls Among Patients With Dizziness
This study found that although meclizine may offer immediate vertigo relief, use is incongruent with guideline-concordant care for common vestibular diagnoses. Receipt of a meclizine prescription was associated with an increased risk of injurious falls among both patients aged 65 years or older and those aged 18 to 64 years with dizziness, who are already fall prone. Future prospective and mechanistic studies may further elucidate the relationship between vestibular suppressants and fall risk, and future guidelines that engage clinicians and patients to deimplement routine vestibular suppressant use for dizziness may be warranted.
Authors
- Schelomo Marmor (ORCID: https://orcid.org/0000-0003-0880-2721)
- Meredith E. Adams (ORCID: https://orcid.org/0000-0002-7962-3475)
- Pinar Karaca‐Mandic (ORCID: https://orcid.org/0000-0002-6682-1982)
Institutions
- University of Minnesota (US)
- University of Michigan (US)
- Michigan Medicine (US)
- Center for Outcomes Research and Clinical Epidemiology (IT)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1001/jamaoto.2025.2052
- Citations
- 2
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.68