Meclizine Use and Subsequent Falls Among Patients With Dizziness

This study found that although meclizine may offer immediate vertigo relief, use is incongruent with guideline-concordant care for common vestibular diagnoses. Receipt of a meclizine prescription was associated with an increased risk of injurious falls among both patients aged 65 years or older and those aged 18 to 64 years with dizziness, who are already fall prone. Future prospective and mechanistic studies may further elucidate the relationship between vestibular suppressants and fall risk, and future guidelines that engage clinicians and patients to deimplement routine vestibular suppressant use for dizziness may be warranted.

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Publication Details

Journal
JAMA Otolaryngology–Head & Neck Surgery
Published
2025-07-24
DOI
https://doi.org/10.1001/jamaoto.2025.2052
Citations
2
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
1.68
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article

Meclizine Use and Subsequent Falls Among Patients With Dizziness

Schelomo Marmor, Meredith E. Adams, Pinar Karaca‐Mandic
2 citations
JAMA Otolaryngology–Head & Neck Surgery
Vestibular and auditory disorders
1.68
article

Meclizine Use and Subsequent Falls Among Patients With Dizziness

Schelomo Marmor, Meredith E. Adams, Pinar Karaca‐Mandic
article en
2 citations

Abstract

This study found that although meclizine may offer immediate vertigo relief, use is incongruent with guideline-concordant care for common vestibular diagnoses. Receipt of a meclizine prescription was associated with an increased risk of injurious falls among both patients aged 65 years or older and those aged 18 to 64 years with dizziness, who are already fall prone. Future prospective and mechanistic studies may further elucidate the relationship between vestibular suppressants and fall risk, and future guidelines that engage clinicians and patients to deimplement routine vestibular suppressant use for dizziness may be warranted.

JAMA Otolaryngology–Head & Neck SurgeryVol. 151(9)
University of Minnesota (US), University of Michigan (US), Michigan Medicine (US), Center for Outcomes Research and Clinical Epidemiology (IT)
Good health and well-being
Openalex Percentile: Top 14%
Vestibular and auditory disorders
1.68
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Meclizine Use and Subsequent Falls Among Patients With Dizziness — Schelomo Marmor, Meredith E. Adams, et al. · JAMA Otolaryngology–Head & Neck Surgery (2025) | TGRS Research Map | TGRS