COLUMBUS part 1–7-year results for encorafenib and binimetinib in BRAF V600-mutant melanoma

This summary presents 7-year results from COLUMBUS part 1, which tested encorafenib (BRAFTOVI®) and binimetinib (MEKTOVI®) (COMBO group), against encorafenib alone (ENCO group), or vemurafenib (ZELBORAF®) alone (VEMU group) as a treatment for a skin cancer called advanced or metastatic BRAF V600-mutant melanoma.

Authors

Institutions

Publication Details

Journal
Future Oncology
Published
2025-07-24
DOI
https://doi.org/10.1080/14796694.2025.2536459
Citations
1
Primary Topic
Melanoma and MAPK Pathways
Type
article
Field-Weighted Citation Impact
0.81

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

COLUMBUS part 1–7-year results for encorafenib and binimetinib in BRAF V600-mutant melanoma

Dirk Schadendorf
1 citations
Future Oncology
Melanoma and MAPK Pathways
0.81
article

COLUMBUS part 1–7-year results for encorafenib and binimetinib in BRAF V600-mutant melanoma

Dirk Schadendorf
article en
1 citations

Abstract

This summary presents 7-year results from COLUMBUS part 1, which tested encorafenib (BRAFTOVI®) and binimetinib (MEKTOVI®) (COMBO group), against encorafenib alone (ENCO group), or vemurafenib (ZELBORAF®) alone (VEMU group) as a treatment for a skin cancer called advanced or metastatic BRAF V600-mutant melanoma.

Future OncologyVol. 21(21)
National Center for Tumor Diseases (DE), Essen University Hospital (DE), University of Duisburg-Essen (DE)
Pfizer, Array BioPharma
Zero hunger
Openalex Percentile: Top 26%
Melanoma and MAPK Pathways
0.81
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.