Creatinine and cystatin C-based indices for predicting sarcopenia, frailty and disability in older community-dwelling adults
Both CCR and SI demonstrate weak diagnostic accuracy for sarcopenia, but their performance in predicting frailty and ADL disability was moderate and comparable among community-dwelling older adults. These findings support further investigation of CCR and SI as biomarkers to help clinicians identify older individuals at risk of adverse clinical outcomes.
Authors
- Weihao Xu (ORCID: https://orcid.org/0000-0002-0213-3144)
- Anying Bai (ORCID: https://orcid.org/0000-0002-3121-1228)
- Jian Cao (ORCID: https://orcid.org/0000-0003-4299-9484)
- Juan Xu (ORCID: https://orcid.org/0000-0003-0469-4356)
- Bei Zhao
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Chinese PLA General Hospital (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Guangdong Academy of Medical Sciences (CN)
Publication Details
- Journal
- The journal of nutrition health & aging
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1016/j.jnha.2025.100635
- Citations
- 3
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Natural Science Foundation of Guangdong Province
- National Natural Science Foundation of China-Guangdong Joint Fund