Ertugliflozin Mitigates Renal Ischemia-Reperfusion Injury through the Downregulation of HIF-1α Expression
Our study provides compelling preliminary evidence that ertugliflozin may improve I/R-induced acute kidney injury by downregulating HIF-1α. This study provides some reference value for the treatment and management of renal I/R injury.
Authors
- Xiangchun Liu (ORCID: https://orcid.org/0000-0001-5822-6094)
- Qian Liu (ORCID: https://orcid.org/0000-0001-8525-7961)
- Shan Li (ORCID: https://orcid.org/0000-0003-1358-4685)
- Mingming Wang (ORCID: https://orcid.org/0000-0002-1787-8720)
- Gang Liu (ORCID: https://orcid.org/0000-0002-3153-7797)
- Yinghui Wang (ORCID: https://orcid.org/0000-0002-9241-394X)
- Qingyuan Wang (ORCID: https://orcid.org/0000-0002-3439-287X)
- Rongyun Su
Institutions
- Shandong University (CN)
- University of Jinan (CN)
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- American Journal of Nephrology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1159/000547539
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00