Loss of DAXX/ATRX Protein Expression Results in Ischemia Resistance and Radiation Sensitivity in Pancreatic Neuroendocrine Tumor Cells and Is Associated with Improved Response to Trans-Arterial Radioembolization
Loss of DAXX/ATRX protein expression is associated with ischemia resistance and radiation sensitivity in Bon-1 and QGP-1 cells and longer LPFS after TARE in PNET patients.
Authors
- Erica S. Alexander (ORCID: https://orcid.org/0000-0001-7880-3565)
- Larissa Shenker
- William-Ray Vista (ORCID: https://orcid.org/0000-0001-5254-2336)
- Lisa Bodei (ORCID: https://orcid.org/0000-0001-6930-7383)
- Adrian J. Gonzalez‐Aguirre (ORCID: https://orcid.org/0000-0002-7604-5788)
- Hooman Yarmohammadi (ORCID: https://orcid.org/0000-0002-3127-9222)
- Mindy K. Graham (ORCID: https://orcid.org/0000-0003-2521-0373)
- Diane Reidy‐Lagunes (ORCID: https://orcid.org/0000-0003-2688-4556)
- A. González Gil (ORCID: https://orcid.org/0000-0002-5802-8028)
- Etay Ziv (ORCID: https://orcid.org/0000-0002-3188-0085)
- James C. Russell (ORCID: https://orcid.org/0000-0002-5901-6416)
- Elena N. Petre
- Joseph P. Erinjeri (ORCID: https://orcid.org/0000-0003-1876-727X)
- J. Puzzuoli (ORCID: https://orcid.org/0000-0003-3187-7086)
- Christopher M. Heaphy (ORCID: https://orcid.org/0000-0003-4264-1810)
- Nitya Raj (ORCID: https://orcid.org/0000-0002-1385-9995)
- Eric Chan
- Jonathan M. Latzman
- Himanshu Narayan Singh (ORCID: https://orcid.org/0000-0003-4111-5165)
- Caleb Solivio
- Anne M. Covey (ORCID: https://orcid.org/0000-0002-1477-8468)
- Gavin Yuan (ORCID: https://orcid.org/0000-0002-7677-012X)
- Anthony Rizzo (ORCID: https://orcid.org/0000-0003-2170-6988)
Institutions
- Boston Medical Center (US)
- Memorial Sloan Kettering Cancer Center (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Neuroendocrinology
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1159/000547041
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00