Prognostic evaluation of molecular endotypes in sepsis: a multicenter cohort study in Brazil

The Mars1 endotype detected by qRT-PCR was associated with worse sepsis survival in low-to middle-income countries. We also identified the Mars 2 endotype as a potential diagnostic marker for sepsis.

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Publication Details

Journal
Shock
Published
2025-06-30
DOI
https://doi.org/10.1097/shk.0000000000002661
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
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article

Prognostic evaluation of molecular endotypes in sepsis: a multicenter cohort study in Brazil

Fernanda do Carmo De Stefani, Igor Alexandre Côrtes de Menezes, Ana Carolina de Miranda, Anelis Maria Marin et al.
1 links
Shock
Bacterial Identification and Susceptibility Testing
article

Prognostic evaluation of molecular endotypes in sepsis: a multicenter cohort study in Brazil

Fernanda do Carmo De Stefani, Igor Alexandre Côrtes de Menezes, Ana Carolina de Miranda, Anelis Maria Marin, Luís Gustavo Morello, Bruna Cassia Dal Vesco, Dalila Lucíola Zanette
article en

Abstract

The Mars1 endotype detected by qRT-PCR was associated with worse sepsis survival in low-to middle-income countries. We also identified the Mars 2 endotype as a potential diagnostic marker for sepsis.

Shock
Universidade Tecnológica Federal do Paraná (BR), Instituto Federal do Paraná (BR), Hospital de Clínicas Universidade Federal do Paraná (BR), Fundação Carlos Chagas (BR), Universidade Federal do Paraná (BR)
No poverty
Openalex Percentile: Top 79%
Bacterial Identification and Susceptibility Testing
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