Multimodal architecture based on dual attention improvement to assist in glaucoma grading challenges

Diabetic glaucoma, a prevalent complication of diabetes, seriously threatens patients' visual health and ranks as a leading cause of irreversible blindness among diabetic individuals. In clinical practice, accurate grading of diabetic glaucoma is crucial for formulating personalized treatment strategies and predicting disease progression. However, existing methods often rely on single - modality data or lack effective integration of multi-modal information, leading to suboptimal grading performance. This study aims to address these issues by presenting two multi-modal disease grading networks enhanced by the cross-attention mechanism for grading diabetic glaucoma using OCT and color fundus images. Two novel cross-attention based image fusion strategies are developed: one employs the multi - head cross - attention mechanism for better inter-modal information fusion, and the other combines self-attention and cross-attention mechanisms. The experimental results show that using the proposed cross attention based method, the Kappa value of multimodal scoring in the GAMMA challenge reaches 84.4%, and the F1 score is 81%. Our work exceeded the performance of the champion and runner up network models in that year's competition. Also, multi-modal grading accuracy shows a 1% - 4% increase compared to single-modality grading. This research not only improves the accuracy of diabetic glaucoma grading but also provides valuable feature support for future multi-task learning models.

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Published
2025-07-24
DOI
https://doi.org/10.1117/12.3069152
Primary Topic
Gaze Tracking and Assistive Technology
Type
article
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article

Multimodal architecture based on dual attention improvement to assist in glaucoma grading challenges

Qichao Dong, Zehao Li, Lin Wang, Ye Wang
Gaze Tracking and Assistive Technology
article

Multimodal architecture based on dual attention improvement to assist in glaucoma grading challenges

Qichao Dong, Zehao Li, Lin Wang, Ye Wang
article en

Abstract

Diabetic glaucoma, a prevalent complication of diabetes, seriously threatens patients' visual health and ranks as a leading cause of irreversible blindness among diabetic individuals. In clinical practice, accurate grading of diabetic glaucoma is crucial for formulating personalized treatment strategies and predicting disease progression. However, existing methods often rely on single - modality data or lack effective integration of multi-modal information, leading to suboptimal grading performance. This study aims to address these issues by presenting two multi-modal disease grading networks enhanced by the cross-attention mechanism for grading diabetic glaucoma using OCT and color fundus images. Two novel cross-attention based image fusion strategies are developed: one employs the multi - head cross - attention mechanism for better inter-modal information fusion, and the other combines self-attention and cross-attention mechanisms. The experimental results show that using the proposed cross attention based method, the Kappa value of multimodal scoring in the GAMMA challenge reaches 84.4%, and the F1 score is 81%. Our work exceeded the performance of the champion and runner up network models in that year's competition. Also, multi-modal grading accuracy shows a 1% - 4% increase compared to single-modality grading. This research not only improves the accuracy of diabetic glaucoma grading but also provides valuable feature support for future multi-task learning models.

People's Liberation Army 401 Hospital (CN), Chinese People's Liberation Army Navy Hospital of Guangzhou (CN), East China Normal University (CN)
Openalex Percentile: Top 82%
Gaze Tracking and Assistive Technology
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Multimodal architecture based on dual attention improvement to assist in glaucoma grading challenges — Qichao Dong, Zehao Li, et al. · (2025) | TGRS Research Map | TGRS