Efficient gene set analysis for DNA methylation addressing probe dependency and bias
These methods are implemented in the R package dmGsea, which is freely available on GitHub and Bioconductor (DOI: 10.18129/B9.bioc.dmGsea). The package supports Illumina 450K, EPIC, and mouse methylation arrays and can be extended to other omics data with user-provided probe-to-gene mapping annotations.
Authors
- Alison A. Motsinger‐Reif (ORCID: https://orcid.org/0000-0003-1346-2493)
- Liang Niu (ORCID: https://orcid.org/0000-0002-2473-9745)
- Zongli Xu (ORCID: https://orcid.org/0000-0002-9034-8902)
Institutions
- National Institute of Environmental Health Sciences (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Bioinformatics
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1093/bioinformatics/btaf422
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Institutes of Health