A comparison of the risk prediction models PERSARC and Sarculator in patients with localized soft tissue sarcoma of the extremities and trunk wall
A high degree of agreement between PERSARC and Sarculator predictions was observed. Patients classified as high-risk by only one method had similar outcomes to those who were high-risk using both. Chemotherapy was associated with improved outcome in the PERSARC, Sarculator, and combined high-risk group. Patients classified as high-risk by one of these methods could be considered for neoadjuvant/adjuvant chemotherapy.
Authors
- Marta Fiocco (ORCID: https://orcid.org/0000-0001-5588-0277)
- Marta Spreafico (ORCID: https://orcid.org/0000-0003-3378-5513)
- Fatih Kızılaslan (ORCID: https://orcid.org/0000-0001-6457-0967)
- Michiel A. J. van de Sande (ORCID: https://orcid.org/0000-0002-9156-7656)
- D. Callegaro
- Kjetil Boye (ORCID: https://orcid.org/0000-0002-5552-6283)
- Ivar Hompland (ORCID: https://orcid.org/0000-0002-7266-4135)
- Alessandro Gronchi (ORCID: https://orcid.org/0000-0002-4703-3534)
- R. Miceli
- M.R. Kobbeltvedt
- Sandro Pasquali (ORCID: https://orcid.org/0000-0003-4815-6293)
- Ingvild Lobmaier
- Dennis P. Swanson
Institutions
- Oslo University Hospital (NO)
- The University of Texas MD Anderson Cancer Center (US)
- University of Oslo (NO)
- Leiden University Medical Center (NL)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1016/j.esmoop.2025.105517
- Citations
- 1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52