Bleeding Due to Vitamin K-Dependent Factor Deficiency in a Patient Taking Topiramate: A Case Report

Topiramate is a well-known medication used for migraine and epilepsy. Bleeding is a rare and less documented side-effect of this treatment. The authors present a rare case of bleeding in a patient who was started on topiramate, which was likely due to a vitamin K-dependent factor deficiency. Clinicians should take caution if any bleeding event is noted in patients on topiramate, and stop administering this drug.

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Publication Details

Journal
EMJ Hematology
Published
2025-07-24
DOI
https://doi.org/10.33590/emjhematol/zyof6655
Primary Topic
Vitamin K Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Bleeding Due to Vitamin K-Dependent Factor Deficiency in a Patient Taking Topiramate: A Case Report

Marcy Canary, Sugam Gouli
EMJ Hematology
Vitamin K Research Studies
article

Bleeding Due to Vitamin K-Dependent Factor Deficiency in a Patient Taking Topiramate: A Case Report

Marcy Canary, Sugam Gouli
article en

Abstract

Topiramate is a well-known medication used for migraine and epilepsy. Bleeding is a rare and less documented side-effect of this treatment. The authors present a rare case of bleeding in a patient who was started on topiramate, which was likely due to a vitamin K-dependent factor deficiency. Clinicians should take caution if any bleeding event is noted in patients on topiramate, and stop administering this drug.

EMJ Hematology
Bassett Medical Center (US)
Openalex Percentile: Top 78%
Vitamin K Research Studies
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Bleeding Due to Vitamin K-Dependent Factor Deficiency in a Patient Taking Topiramate: A Case Report — Marcy Canary, Sugam Gouli · EMJ Hematology (2025) | TGRS Research Map | TGRS