I2-DMSO-Mediated Three-Component Cyclization of 2-Aminobenzimidazole to Access 2,3-Substituted Benzo[4,5]imidazo[1,2-a]pyrimidine Derivatives
Abstract An I2-DMSO-mediated, one-pot synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine-2,3-diylbis(phenylmethyl ketone) derivatives have been developed using 2-aminobenzimidazole, acetophenone, and enaminone as starting materials. The structures of the compounds were characterized by single-crystal X-ray diffraction.
Authors
- Jianyong Yuan (ORCID: https://orcid.org/0000-0002-3212-6236)
- Shengliang Liao (ORCID: https://orcid.org/0000-0002-1622-563X)
- Qian Guo (ORCID: https://orcid.org/0000-0002-2133-5358)
- Mengyi Guo
- Luoteng Cheng
- Wei Yuan (ORCID: https://orcid.org/0009-0008-1630-2085)
Institutions
- Chongqing Maternal and Child Health Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Synthesis
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1055/a-2631-4457
- Primary Topic
- Synthesis and Biological Evaluation
- Type
- article
- Field-Weighted Citation Impact
- 0.00