FedGAN: Federated diabetic retinopathy image generation

Deep learning models for diagnostic applications require large amounts of sensitive patient data, raising privacy concerns under centralized training paradigms. We propose FedGAN, a federated learning framework for synthetic medical image generation that combines Generative Adversarial Networks (GANs) with cross-silo federated learning. Our approach pretrains a DCGAN on abdominal CT scans and fine-tunes it collaboratively across clinical silos using diabetic retinopathy datasets. By federating the GAN's discriminator and generator via the Federated Averaging (FedAvg) algorithm, FedGAN generates high-quality synthetic retinal images while complying with HIPAA and GDPR. Experiments demonstrate that FedGAN achieves a realism score of 0.43 (measured by a centralized discriminator). This work bridges data scarcity and privacy challenges in medical AI, enabling secure collaboration across institutions.

Authors

Institutions

Publication Details

Journal
PLoS ONE
Published
2025-07-24
DOI
https://doi.org/10.1371/journal.pone.0326579
Citations
5
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
6.80

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

FedGAN: Federated diabetic retinopathy image generation

H Kamran, Nouf Nawar Alotaibi, Mrim M. Alnfiai, Sohaib Latif et al.
5 citations
PLoS ONE
Retinal Imaging and Analysis
6.80
article

FedGAN: Federated diabetic retinopathy image generation

H Kamran, Nouf Nawar Alotaibi, Mrim M. Alnfiai, Sohaib Latif, Syed Jawad Hussain, Imtiaz Ali Soomro
article en
5 citations

Abstract

Deep learning models for diagnostic applications require large amounts of sensitive patient data, raising privacy concerns under centralized training paradigms. We propose FedGAN, a federated learning framework for synthetic medical image generation that combines Generative Adversarial Networks (GANs) with cross-silo federated learning. Our approach pretrains a DCGAN on abdominal CT scans and fine-tunes it collaboratively across clinical silos using diabetic retinopathy datasets. By federating the GAN's discriminator and generator via the Federated Averaging (FedAvg) algorithm, FedGAN generates high-quality synthetic retinal images while complying with HIPAA and GDPR. Experiments demonstrate that FedGAN achieves a realism score of 0.43 (measured by a centralized discriminator). This work bridges data scarcity and privacy challenges in medical AI, enabling secure collaboration across institutions.

PLoS ONEVol. 20(7)
Taif University (SA), University College of Islamabad (PK), Najran University (SA)
Taif University
Reduced inequalities
Openalex Percentile: Top 3%
Retinal Imaging and Analysis
6.80
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.