Sputum and Tongue Swab Molecular Testing for the In-Home Diagnosis of Tuberculosis in Unselected Household Contacts: A Cost and Cost-Effectiveness Analysis
In-home POC molecular TB testing strategies that use combination testing of tongue swabs and sputum specimens can meaningfully improve the number of people tested, diagnosed, and notified during household contact investigation while being cost-effective.
Authors
- Andrew Medina‐Marino (ORCID: https://orcid.org/0000-0002-0095-4141)
- Gesine Meyer‐Rath (ORCID: https://orcid.org/0000-0003-0439-381X)
- Sharon Olifant (ORCID: https://orcid.org/0000-0003-0853-2207)
- Charl Bezuidenhout
- Morten Rühwald (ORCID: https://orcid.org/0000-0002-1597-441X)
- Lawrence Long (ORCID: https://orcid.org/0000-0003-4986-4988)
- Matthew P. Fox (ORCID: https://orcid.org/0000-0001-9887-0634)
- Grant Theron (ORCID: https://orcid.org/0000-0002-9216-2415)
- Adam Penn‐Nicholson (ORCID: https://orcid.org/0000-0002-1883-0059)
- P. Bernard Fourie (ORCID: https://orcid.org/0000-0002-1630-3554)
- Brooke E Nichols (ORCID: https://orcid.org/0000-0003-4682-4999)
Institutions
- South African Medical Research Council (ZA)
- Boston University (US)
- FIND (CH)
- Desmond Tutu HIV Foundation (ZA)
- University of Cape Town (ZA)
- University of the Witwatersrand (ZA)
- Stellenbosch University (ZA)
- Amsterdam Institute for Global Health and Development (NL)
- University of Pretoria (ZA)
- University of Pennsylvania (US)
- National Research Foundation (ZA)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1093/cid/ciaf389
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79