Can Tirzepatide Revolutionize Gastric Cancer Prevention? A Comprehensive Analysis

Abstract With the introduction of new drugs like tirzepatide, the relationship between metabolic treatments and oncology has attracted a lot of interest lately. Tirzepatide, a dual agonist of glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptors, has shown promising results in the treatment of type 2 diabetes and obesity, two disorders associated with an increased risk of gastric cancer. The purpose of this study is to examine tirzepatide's possible effects on the development and prevention of stomach cancer. We investigate the therapeutic potential of tirzepatide and pinpoint areas in need of more investigation by looking at the body of existing literature and mechanistic insights . The results emphasize the need [1] , [3] for more research into tirzepatide's direct impact on gastric carcinogenesis as well as its complex modes of action and function in modifying risk factors.

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Publication Details

Journal
Internal Medicine
Published
2025-01-01
DOI
https://doi.org/10.2478/inmed-2025-0318
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
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article

Can Tirzepatide Revolutionize Gastric Cancer Prevention? A Comprehensive Analysis

Mihaela Cristina Brisc, Ciprian Brisc, Alexandra Orășeanu, Horia Popa et al.
Internal Medicine
Gastric Cancer Management and Outcomes
article

Can Tirzepatide Revolutionize Gastric Cancer Prevention? A Comprehensive Analysis

Mihaela Cristina Brisc, Ciprian Brisc, Alexandra Orășeanu, Horia Popa, Sabina Florina Șolea, Amina Venter
article en

Abstract

Abstract With the introduction of new drugs like tirzepatide, the relationship between metabolic treatments and oncology has attracted a lot of interest lately. Tirzepatide, a dual agonist of glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptors, has shown promising results in the treatment of type 2 diabetes and obesity, two disorders associated with an increased risk of gastric cancer. The purpose of this study is to examine tirzepatide's possible effects on the development and prevention of stomach cancer. We investigate the therapeutic potential of tirzepatide and pinpoint areas in need of more investigation by looking at the body of existing literature and mechanistic insights . The results emphasize the need [1] , [3] for more research into tirzepatide's direct impact on gastric carcinogenesis as well as its complex modes of action and function in modifying risk factors.

Internal MedicineVol. 22(1)
University of Oradea (RO), Clinical Emergency Hospital Bucharest (RO)
Openalex Percentile: Top 72%
Gastric Cancer Management and Outcomes
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Can Tirzepatide Revolutionize Gastric Cancer Prevention? A Comprehensive Analysis — Mihaela Cristina Brisc, Ciprian Brisc, et al. · Internal Medicine (2025) | TGRS Research Map | TGRS