Performance of enhanced liver fibrosis test and indirect serum fibrosis markers for exclusion of advanced liver fibrosis in alpha-1 antitrypsin deficiency
In Pi*ZZ AATD patients APRI below 0.41 or FIB-4 below 1.79 excludes advanced fibrosis/cirrhosis if TE in unavailable, ELF had no additional value. TE remains the preferred method for staging fibrosis in AATD.
Authors
- Malin Fromme (ORCID: https://orcid.org/0000-0003-0382-5705)
- Pavel Strnad (ORCID: https://orcid.org/0000-0002-7122-6379)
- Jan Stolk (ORCID: https://orcid.org/0000-0002-7887-386X)
- Ilaria Ferrarotti (ORCID: https://orcid.org/0000-0003-4892-4192)
- Bart van Hoek (ORCID: https://orcid.org/0000-0001-6527-764X)
- Naomi Kappe (ORCID: https://orcid.org/0000-0003-4614-1477)
Institutions
- University of Pavia (IT)
- Leiden University Medical Center (NL)
- RWTH Aachen University (DE)
Publication Details
- Journal
- European Journal of Internal Medicine
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1016/j.ejim.2025.07.019
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71