Diabetes is associated with a decreased risk of meningiomas: a mendelian randomization study
Our results suggest that T1DM and T2DM correlate with a lower risk of benign cerebral and malignant meningiomas. We also identify BMI as a risk factor of meningiomas and as a confounder. These insights into the interplay between T2DM, obesity and meningiomas provide a better foundation to understand the complex underlying biology and pathophysiology of meningiomas.
Authors
- Tiit Illimar Mathiesen (ORCID: https://orcid.org/0000-0001-9463-1919)
- Andrea Daniela Maier (ORCID: https://orcid.org/0000-0002-5930-0636)
- Christian Mirian (ORCID: https://orcid.org/0000-0001-6801-0123)
- Anders Broechner (ORCID: https://orcid.org/0000-0001-9195-6726)
- Ruikang K. Wang (ORCID: https://orcid.org/0000-0001-5169-8822)
Institutions
- Copenhagen University Hospital (DK)
Publication Details
- Journal
- Journal of Clinical Neuroscience
- Published
- 2025-07-24
- DOI
- https://doi.org/10.1016/j.jocn.2025.111519
- Citations
- 1
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Lundbeckfonden
- H. Lundbeck A/S