Chloride-to-(radio)iodide exchange on NHC–metal complexes
Efficient chloride/iodide exchange on chloro-NHC-metal complexes was achieved under mild conditions using stable or radioactive iodide. The protocol enables simultaneous synthesis of radiolabeled compounds and their non-radioactive references, facilitating the development of chemically matched theranostic pairs.
Authors
- Anaïs Prigent
- Gauthier Foucras
- Thomas Cailly (ORCID: https://orcid.org/0000-0002-5262-4494)
- Ginevra Giobbio
- Sylvain Gaillard (ORCID: https://orcid.org/0000-0003-3402-2518)
- Killian Henault (ORCID: https://orcid.org/0009-0007-8851-3212)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Centre François Baclesse (LU)
- Normandie Université (FR)
- Centre Hospitalier Universitaire de Caen Normandie (FR)
- Centre François Baclesse (FR)
- Cyceron (FR)
- Centre d'Etudes et de Recherche sur le Médicament de Normandie
- Université de Rouen Normandie (FR)
- Institut National des Sciences Appliquées Rouen Normandie (FR)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- Dalton Transactions
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5dt01364j
- Primary Topic
- Chemical Synthesis and Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.00