Differential resting-state functional connectivity patterns in functional movement disorders: Evidence for gait-disorder-specific aberrations

Our findings suggest distinct neurobiological signatures in functional gait disorders compared to other functional movement phenotypes. These findings might reflect specific pathophysiological mechanisms underlying functional gait disorders, particularly involving sensory feedback integration and motor control. These results provide new insights into the neurobiological basis of different FMD phenotypes and may contribute to the development of targeted therapeutic approaches.

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Publication Details

Journal
NeuroImage Clinical
Published
2025-01-01
DOI
https://doi.org/10.1016/j.nicl.2025.103850
Citations
1
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
1.43

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article

Differential resting-state functional connectivity patterns in functional movement disorders: Evidence for gait-disorder-specific aberrations

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NeuroImage Clinical
Functional Brain Connectivity Studies
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article

Differential resting-state functional connectivity patterns in functional movement disorders: Evidence for gait-disorder-specific aberrations

Christian Erdmann, Stephan Wolff, Jos Becktepe, Alexander Maximilian Münchau, Philipp Koch, Johanna Geritz, Carl Alexander Gless, Oliver Granert, Annemarie Reincke, Anne Weißbach, Christina Bolte, Norbert Brüggemann, Christof Degen-Plöger, Svea Seehafer, Kirsten E. Zeuner
article en
1 citations

Abstract

Our findings suggest distinct neurobiological signatures in functional gait disorders compared to other functional movement phenotypes. These findings might reflect specific pathophysiological mechanisms underlying functional gait disorders, particularly involving sensory feedback integration and motor control. These results provide new insights into the neurobiological basis of different FMD phenotypes and may contribute to the development of targeted therapeutic approaches.

NeuroImage ClinicalVol. 48
Christian-Albrechts-Universität zu Kiel (DE), University of Lübeck (DE)
Deutsche Forschungsgemeinschaft
Reduced inequalities
Openalex Percentile: Top 17%
Functional Brain Connectivity Studies
1.43
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