Distinct molecular profile and outcome of oligodendroglioma, <i>IDH</i> -mutant, 1p/19q-codeleted, and <i>TERT</i> p-wildtype: A grade 1 oligodendroglioma of young patients?

In conclusion, "oligodendroglioma, IDH-mutant, 1p/19q-codeleted, and TERTp-wildtype" represent a distinct molecular subgroup associated with younger age and a better clinical course compared to CNS WHO grade 2 oligodendrogliomas.

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Publication Details

Journal
Neuro-Oncology
Published
2025-07-19
DOI
https://doi.org/10.1093/neuonc/noaf141
Citations
2
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
3.25
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article

Distinct molecular profile and outcome of oligodendroglioma, IDH -mutant, 1p/19q-codeleted, and TERT p-wildtype: A grade 1 oligodendroglioma of young patients?

L. Friedrich, Sandro M. Krieg, Abigail K. Suwala, Alessandra Macciotta et al.
2 citations
Neuro-Oncology
Glioma Diagnosis and Treatment
3.25
article

Distinct molecular profile and outcome of oligodendroglioma, IDH -mutant, 1p/19q-codeleted, and TERT p-wildtype: A grade 1 oligodendroglioma of young patients?

L. Friedrich, Sandro M. Krieg, Abigail K. Suwala, Alessandra Macciotta, Leonille Schweizer, Sabrina Zechel, Philippe Schucht, Theoni Maragkou, Christel C. Herold‐Mende, Ramin Rahmanzade, Luca Bertero, Benjamin Goeppert, Jordan R. Hansford, Gudrun Fleischhack, Daniel Schrimpf, Christine Stadelmann, Jens Schittenhelm, Rouzbeh Banan, Stefan M. Pfister, Roland Coras, Philipp Sievers, Felix Hinz, Kathy Keyvani, Simone Schmid, Oliver Werner Sakowitz, Filippo Nozzoli, Andreas von Deimling, Matthias Meinhardt, David Reuß, Dong-Anh Khuong-Quang, Felix Sahm, Simona Osella‐Abate, Dennis Friedel, Alessia Andrea Ricci, Tareq Adnan Juratli, Thorsten Simon, Fuat Kaan Aras, Wolfgang Wick, Stefan Pusch, Henri Bogumil, Miriam Ratliff, Nima Etminan, Kirsten Göbel
article en
2 citations

Abstract

In conclusion, "oligodendroglioma, IDH-mutant, 1p/19q-codeleted, and TERTp-wildtype" represent a distinct molecular subgroup associated with younger age and a better clinical course compared to CNS WHO grade 2 oligodendrogliomas.

Neuro-OncologyVol. 27(10)
Goethe University Frankfurt (DE), University of Bern (CH), Royal Children's Hospital (AU), German Cancer Research Center (DE), University of Cologne (DE), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Heidelberg University (DE), University Hospital of Bern (CH), Women's and Children's Hospital (AU), University Hospital Heidelberg (DE), Humboldt-Universität zu Berlin (DE), Universitätsklinikum Erlangen (DE), Universitätsklinikum Tübingen (DE), National Center for Tumor Diseases (DE), Azienda Ospedaliero-Universitaria Careggi (IT), Universitätsmedizin Göttingen (DE), Hopp Children's Cancer Center Heidelberg (DE), Essen University Hospital (DE), University Children's Hospital Tübingen (DE), Department of Medical Sciences (BY), University Hospital Frankfurt (DE), South Australian Health and Medical Research Institute (AU), Centre for Cancer Biology (AU), Klinikum Ludwigsburg (DE), Murdoch Children's Research Institute (AU), Piedmont Reference Center for Epidemiology and Cancer Prevention (IT), University Hospital Cologne (DE), University Medical Centre Mannheim (DE), Frankfurt Cancer Institute (DE), University Hospital Carl Gustav Carus (DE), University of Florence (IT), University of Turin (IT), The University of Adelaide (AU), University of Duisburg-Essen (DE), University of Göttingen (DE), University of Tübingen (DE), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 8%
Glioma Diagnosis and Treatment
3.25
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