FMO5 Plays a Sex-specific Role in Goblet Cell Maturation and Mucus Barrier Formation
Together, our results identify a highly conserved and novel role for FMO5 in the mammalian intestine and support a key role for FMO5 in maintenance of ER/protein homeostasis and proper mucus barrier formation.
Authors
- Scott F. Leiser (ORCID: https://orcid.org/0000-0002-8003-2955)
- Joy Mecano
- Ryan J. Rebernick (ORCID: https://orcid.org/0000-0002-5532-581X)
- Yatrik M. Shah (ORCID: https://orcid.org/0000-0002-2487-4816)
- Sumeet Solanki (ORCID: https://orcid.org/0000-0002-2773-3082)
- Safa Beydoun (ORCID: https://orcid.org/0000-0001-8068-3953)
- Wesley Huang (ORCID: https://orcid.org/0000-0003-0551-8397)
- Megan L. Schaller (ORCID: https://orcid.org/0000-0003-4347-8701)
- Amara Bugarin-Lapuz
- Emily Wang (ORCID: https://orcid.org/0009-0008-9288-6860)
- M Sykes
Institutions
- University of Michigan (US)
- Michigan Medicine (US)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101591
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Glenn Foundation for Medical Research
- Fondation pour la Recherche Médicale
- National Institutes of Health
- National Institute on Aging
- National Cancer Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute of Child Health and Human Development