Association between the rs2279238 and rs12221497 of the LXRA gene variants and diabetic retinopathy in the Slovenian cohort
The rs2279238 variant in the LXRA gene is significantly associated with diabetic retinopathy (DR) in Caucasians with T2DM. Individuals carrying the TT or TC genotype have a higher risk of developing DR compared to those with the CC genotype. However, no association was found between the rs12221497 variant and DR.
Authors
- Daniel Petrovič (ORCID: https://orcid.org/0000-0001-6637-2542)
- Ines Cilenšek (ORCID: https://orcid.org/0000-0002-1702-7715)
- Mojca Globočnik Petrovič
- Izabella Karska‐Basta (ORCID: https://orcid.org/0000-0001-7927-6277)
- Emin Grbić
- Jernej Letonja (ORCID: https://orcid.org/0000-0002-1473-3534)
Institutions
- Jagiellonian University (PL)
- University of Tuzla (BA)
- University of Ljubljana (SI)
- Ljubljana University Medical Centre (SI)
Publication Details
- Journal
- Gene
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1016/j.gene.2025.149665
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 0.00