Comparative Response of Immune System Activation in Patients in the Postoperative Period: A Study of Antibacterial Therapy versus Radonized Water from Tskaltubo

Tskaltubo radon-rich mineral water produced a different immunological profile. While similarly effective in suppressing pathogenic flora, this intervention preserved and possibly enhanced the mucosal immune response. In Group 2, patients exhibited increased levels of interferon-gamma (IFN-γ) and interleukin-4 (IL-4), without a corresponding rise in proinflammatory cytokines such as IL-1 or IL-6. This indicates a measured activation of the immune system in response to surgical trauma. Most notably, IL-10 levels increased in this group, suggesting a heightened regulatory response and a more balanced immune environment conducive to controlled healing.