Postpartum Hemorrhage: Evidence-Based Prophylaxis

Postpartum hemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide, particularly in low-and middle-income countries.This article critically reviews pharmacological, mechanical and organizational prophylactic interventions aimed at reducing the incidence and severity of PPH.The administration of uterotonics, particularly oxytocin and misoprostol, combined with active management of the third stage of labor and the use of intrauterine tamponade devices, has shown effectiveness in immediate hemostasis and reduction of long-term complications.Standardized institutional protocols and obstetric emergency training are essential to optimize early recognition and rapid treatment of PPH, significantly improving clinical outcomes and maternal safety.

Authors

Publication Details

Journal
Medical & Clinical Case Reports Journal
Published
2025-06-30
DOI
https://doi.org/10.51219/mccrj/gabriela-siviero-mendes/278
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
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article

Postpartum Hemorrhage: Evidence-Based Prophylaxis

Paulo Ayroza Ribeiro, Vera Lúcia Duarte da Costa Mendes, Hiroaki Murata, Beatriz Martins Guerra Pantuza Almeida et al.
Medical & Clinical Case Reports Journal
Maternal and fetal healthcare
article

Postpartum Hemorrhage: Evidence-Based Prophylaxis

Paulo Ayroza Ribeiro, Vera Lúcia Duarte da Costa Mendes, Hiroaki Murata, Beatriz Martins Guerra Pantuza Almeida, Gabriela Siviero Mendes, G Leal, Edmilson Cunha de Camargo, Amanda Marutti Feltrin, Karolina Bogusch Cava, Pedro Henrique Rios Registro, Lays Barbosa Stival, Victor Hugo Correia Saibert Freire
article en

Abstract

Postpartum hemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide, particularly in low-and middle-income countries.This article critically reviews pharmacological, mechanical and organizational prophylactic interventions aimed at reducing the incidence and severity of PPH.The administration of uterotonics, particularly oxytocin and misoprostol, combined with active management of the third stage of labor and the use of intrauterine tamponade devices, has shown effectiveness in immediate hemostasis and reduction of long-term complications.Standardized institutional protocols and obstetric emergency training are essential to optimize early recognition and rapid treatment of PPH, significantly improving clinical outcomes and maternal safety.

Medical & Clinical Case Reports JournalVol. 3(2)
Openalex Percentile: Top 75%
Maternal and fetal healthcare
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