MLM4SynMed: Masked Language Modelling for Synthetic Free-text Medical Records Generation

In this paper, we systematically investigate the possibility, quality, and potential usage of generating synthetic free-text medical records, such as discharge summaries, admission notes, and doctor correspondences, using the Masked Language Modelling (MLM) strategy. Our system is designed to preserve the critical information of the records while introducing significant diversity and minimising re-identification risk. The system incorporates a de-identification component that uses Philter to mask Protected Health Information (PHI), followed by a Medical Entity Recognition (NER) model to retain key medical information. We explore various masking ratios and mask-filling techniques to balance the trade-off between diversity and fidelity in the synthetic outputs without affecting overall readability. Our results demonstrate that the system can produce high-quality synthetic data with significant diversity while achieving a HIPAA-compliant PHI recall rate of 0.96 and a low re-identification risk of 0.035. Furthermore, downstream evaluations using an NER task reveal that the synthetic data can be effectively used to train models with performance comparable to those trained on real data. The flexibility of the system allows it to be adapted for specific use cases, making it a valuable tool for privacy-preserving data generation in medical research and healthcare applications. We host our models and data publicly at https://github.com/HECTA-UoM/MLM4SynMed

Authors

Institutions

Publication Details

Published
2025-06-18
DOI
https://doi.org/10.1109/ichi64645.2025.00067
Primary Topic
Topic Modeling
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

MLM4SynMed: Masked Language Modelling for Synthetic Free-text Medical Records Generation

Goran Nenadić, Nicolo Micheletti, Libo Ren, Lifeng Han et al.
Topic Modeling
article

MLM4SynMed: Masked Language Modelling for Synthetic Free-text Medical Records Generation

Goran Nenadić, Nicolo Micheletti, Libo Ren, Lifeng Han, Samuel Belkadi
article en

Abstract

In this paper, we systematically investigate the possibility, quality, and potential usage of generating synthetic free-text medical records, such as discharge summaries, admission notes, and doctor correspondences, using the Masked Language Modelling (MLM) strategy. Our system is designed to preserve the critical information of the records while introducing significant diversity and minimising re-identification risk. The system incorporates a de-identification component that uses Philter to mask Protected Health Information (PHI), followed by a Medical Entity Recognition (NER) model to retain key medical information. We explore various masking ratios and mask-filling techniques to balance the trade-off between diversity and fidelity in the synthetic outputs without affecting overall readability. Our results demonstrate that the system can produce high-quality synthetic data with significant diversity while achieving a HIPAA-compliant PHI recall rate of 0.96 and a low re-identification risk of 0.035. Furthermore, downstream evaluations using an NER task reveal that the synthetic data can be effectively used to train models with performance comparable to those trained on real data. The flexibility of the system allows it to be adapted for specific use cases, making it a valuable tool for privacy-preserving data generation in medical research and healthcare applications. We host our models and data publicly at https://github.com/HECTA-UoM/MLM4SynMed

University of Cambridge (GB), University of Manchester (GB)
UK Research and Innovation, European Commission, HORIZON EUROPE Framework Programme, Engineering and Physical Sciences Research Council, Innovate UK
Quality Education
Openalex Percentile: Top 91%
Topic Modeling
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

MLM4SynMed: Masked Language Modelling for Synthetic Free-text Medical Records Generation — Goran Nenadić, Nicolo Micheletti, et al. · (2025) | TGRS Research Map | TGRS