BAP1 complexes with YY1 and RBBP7 and its downstream targets in ccRCC cells
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer. A few genes, such as <i>BAP1</i>, are associated with the tumorigenesis of ccRCC. Mutations in <i>BAP1</i> are related to a proportion of ccRCCs. In this study, to explore the functional role of <i>BAP1</i> in ccRCC, the potential interacting proteins with <i>BAP1</i> in ccRCC cells are to be identified, and the gene expression profiles of <i>BAP1</i> knockdown 786-O cells are to be analyzed.
Authors
- You Fu Pan (ORCID: https://orcid.org/0000-0002-9996-8892)
- Xueying Li (ORCID: https://orcid.org/0000-0003-1984-3609)
- Ying Wu (ORCID: https://orcid.org/0000-0001-5218-2983)
- Jindong Chen (ORCID: https://orcid.org/0000-0003-4551-2344)
Institutions
- Zunyi Medical University (CN)
- Guizhou Provincial Education Department (CN)
- Department of Health of Guangdong Province (CN)
Publication Details
- Journal
- Open Life Sciences
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1515/biol-2025-1140
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China