Dual antiplatelet therapy practices following Pipeline Shield embolization and their impact on adverse events in three large real-life registries

In this large real-world retrospective analysis, most major adverse events were reported within 30 days post-FDS procedure. Complications rates after discharge and after DAPT discontinuation were very low and similar between DAPT duration groups. These data provide a foundation for designing future prospective studies to evaluate optimal DAPT protocols-both in terms of drug type and duration-which could potentially inform future clinical guidelines.

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Publication Details

Journal
Journal of Neuroradiology
Published
2025-07-19
DOI
https://doi.org/10.1016/j.neurad.2025.101372
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

Dual antiplatelet therapy practices following Pipeline Shield embolization and their impact on adverse events in three large real-life registries

Cristian Mihalea, Laurent Spelle, Saleh Lamin, Jildaz Caroff et al.
Journal of Neuroradiology
Venous Thromboembolism Diagnosis and Management
article

Dual antiplatelet therapy practices following Pipeline Shield embolization and their impact on adverse events in three large real-life registries

Cristian Mihalea, Laurent Spelle, Saleh Lamin, Jildaz Caroff, Markus Holtmannspötter, Mario Martínez‐Galdámez, Jens Fiehler
article en

Abstract

In this large real-world retrospective analysis, most major adverse events were reported within 30 days post-FDS procedure. Complications rates after discharge and after DAPT discontinuation were very low and similar between DAPT duration groups. These data provide a foundation for designing future prospective studies to evaluate optimal DAPT protocols-both in terms of drug type and duration-which could potentially inform future clinical guidelines.

Journal of NeuroradiologyVol. 52(5)
Universidad de Valladolid (ES), Inserm (FR), Universität Hamburg (DE), Université Paris-Saclay (FR), Queen Elizabeth Hospital Birmingham (GB), Victor Babeș University of Medicine and Pharmacy Timișoara (RO), University Medical Center Hamburg-Eppendorf (DE), Paracelsus Medizinische Privatuniversität (DE), Bicêtre Hospital (FR)
Openalex Percentile: Top 67%
Venous Thromboembolism Diagnosis and Management
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