Colorimetric ALP detection with a ligand-exchanged Au<sub>8</sub> cluster
An atomically precise Au<sub>8</sub> nanocluster (dppm/dppp) synthesized <i>via</i> ligand exchange exhibits oxidase-like activity. Alkaline phosphatase (ALP) quenches O<sub>2</sub>˙<sup>-</sup>, enabling sensitive and specific colorimetric detection and demonstrating diagnostic potential.
Authors
- Man‐Bo Li (ORCID: https://orcid.org/0000-0002-6265-3045)
- Jingjing Yang (ORCID: https://orcid.org/0000-0001-8920-3477)
- Hongliang Zhao
- Ming Yao (ORCID: https://orcid.org/0000-0001-9553-8214)
- Yan Zhao (ORCID: https://orcid.org/0000-0002-5491-1227)
- Yu Cheng (ORCID: https://orcid.org/0000-0002-9030-2023)
- John J. Ruan (ORCID: https://orcid.org/0000-0001-8665-5523)
- Qian Wang (ORCID: https://orcid.org/0000-0002-2149-384X)
- Zhikun Wu (ORCID: https://orcid.org/0000-0002-2711-3860)
- Qing You (ORCID: https://orcid.org/0000-0002-9352-8052)
Institutions
- Anhui University (CN)
- Hefei Institutes of Physical Science (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc02136g
- Citations
- 2
- Primary Topic
- Nanocluster Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.04