A Rare Case of Isolated Invasive Aspergillosis of Vocal Cord in an Immunocompromised Patient: Case Report

described aspergillosis and named it because of its resemblance to "rougher head."Bearing of asexual spores is the most important character in Aspergillus taxonomy and is recognized by circular, IntroductIonFungal laryngitis with isolated involvement of the vocal cords is a rare clinical entity with very few cases reported in the literature.Candida is the most common pathogen involved followed by Aspergillus species.The clinical presentation includes nonspecific symptoms such as hoarseness of voice, breathlessness, foreign body sensation in the throat, and sometimes dysphagia.Predisposing factors such as immunodeficiency states, laryngopharyngeal reflux disease, prolonged antibiotic ingestion, 1-4 and occupational exposure to cow dung and animal dander as in farming play a major role in the causation of fungal infections of the respiratory tract.Iatrogenic factors such as radiotherapy, chronic steroid inhalation, and laser treatment may predispose to localized fungal laryngitis. 5he common species attributed to fungal laryngitis includes Aspergillus, Candida, Histoplasma, Cryptococcus, and Blastomyces. 1,4he nonspecific presentation and mimicking of other laryngeal conditions lead to misdiagnosis and inappropriate treatment.A high index of suspicion is required for diagnosis, and prompt treatment with antifungals is crucial for alleviation of symptoms.Aspergillus is a term used to name a genus of fungi that bear asexual spores and reproduce only asexually.

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Publication Details

Journal
International Journal of Phonosurgery & Laryngology
Published
2025-07-20
DOI
https://doi.org/10.5005/jp-journals-10023-1271
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

A Rare Case of Isolated Invasive Aspergillosis of Vocal Cord in an Immunocompromised Patient: Case Report

Susan K. Mathai, Navin Nagaraj
International Journal of Phonosurgery & Laryngology
Antifungal resistance and susceptibility
article

A Rare Case of Isolated Invasive Aspergillosis of Vocal Cord in an Immunocompromised Patient: Case Report

Susan K. Mathai, Navin Nagaraj
article en

Abstract

described aspergillosis and named it because of its resemblance to "rougher head."Bearing of asexual spores is the most important character in Aspergillus taxonomy and is recognized by circular, IntroductIonFungal laryngitis with isolated involvement of the vocal cords is a rare clinical entity with very few cases reported in the literature.Candida is the most common pathogen involved followed by Aspergillus species.The clinical presentation includes nonspecific symptoms such as hoarseness of voice, breathlessness, foreign body sensation in the throat, and sometimes dysphagia.Predisposing factors such as immunodeficiency states, laryngopharyngeal reflux disease, prolonged antibiotic ingestion, 1-4 and occupational exposure to cow dung and animal dander as in farming play a major role in the causation of fungal infections of the respiratory tract.Iatrogenic factors such as radiotherapy, chronic steroid inhalation, and laser treatment may predispose to localized fungal laryngitis. 5he common species attributed to fungal laryngitis includes Aspergillus, Candida, Histoplasma, Cryptococcus, and Blastomyces. 1,4he nonspecific presentation and mimicking of other laryngeal conditions lead to misdiagnosis and inappropriate treatment.A high index of suspicion is required for diagnosis, and prompt treatment with antifungals is crucial for alleviation of symptoms.Aspergillus is a term used to name a genus of fungi that bear asexual spores and reproduce only asexually.

International Journal of Phonosurgery & LaryngologyVol. 15(2)
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Openalex Percentile: Top 78%
Antifungal resistance and susceptibility
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A Rare Case of Isolated Invasive Aspergillosis of Vocal Cord in an Immunocompromised Patient: Case Report — Susan K. Mathai, Navin Nagaraj · International Journal of Phonosurgery & Laryngology (2025) | TGRS Research Map | TGRS