Case Report of a Non-Small-Cell Lung Cancer Patient with Cytotoxic Chemotherapy-Induced Neutropenia Treated with Korean Medicine

Objectives: To report a case of non-small-cell lung cancer (NSCLC) with chemotherapy-induced neutropenia that improved following Korean medicine treatment.Methods: After developing neutropenia following the first cycle of cytotoxic chemotherapy, a patient with NSCLC received Korean medicine treatment including herbal medicine (<i>Ikgibohyeol-tang</i>) and acupuncture. To evaluate the therapeutic effect, changes in ANC levels and G-CSF dosage were assessed along with tumor response via computed tomography and magnetic resonance imaging and symptom changes using the FACT-L questionnaire.Results: After treatment, the patient showed improvement in the severity grade of neutropenia and lower G-CSF usage. The tumor size reduced, and the FACT-L score improved slightly.Conclusion: This case suggests that Korean medicine treatment may serve as a supportive therapy for managing chemotherapy-induced neutropenia in cancer patients.

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Publication Details

Journal
The Journal of Internal Korean Medicine
Published
2025-06-30
DOI
https://doi.org/10.22246/jikm.2025.46.3.521
Primary Topic
Mycobacterium research and diagnosis
Type
article
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article

Case Report of a Non-Small-Cell Lung Cancer Patient with Cytotoxic Chemotherapy-Induced Neutropenia Treated with Korean Medicine

Don-Hyun Choi, Min-Seob Lee, lew jaehwan, Su-hyun Chin
The Journal of Internal Korean Medicine
Mycobacterium research and diagnosis
article

Case Report of a Non-Small-Cell Lung Cancer Patient with Cytotoxic Chemotherapy-Induced Neutropenia Treated with Korean Medicine

Don-Hyun Choi, Min-Seob Lee, lew jaehwan, Su-hyun Chin
article en

Abstract

Objectives: To report a case of non-small-cell lung cancer (NSCLC) with chemotherapy-induced neutropenia that improved following Korean medicine treatment.Methods: After developing neutropenia following the first cycle of cytotoxic chemotherapy, a patient with NSCLC received Korean medicine treatment including herbal medicine (<i>Ikgibohyeol-tang</i>) and acupuncture. To evaluate the therapeutic effect, changes in ANC levels and G-CSF dosage were assessed along with tumor response via computed tomography and magnetic resonance imaging and symptom changes using the FACT-L questionnaire.Results: After treatment, the patient showed improvement in the severity grade of neutropenia and lower G-CSF usage. The tumor size reduced, and the FACT-L score improved slightly.Conclusion: This case suggests that Korean medicine treatment may serve as a supportive therapy for managing chemotherapy-induced neutropenia in cancer patients.

The Journal of Internal Korean MedicineVol. 46(3)
Openalex Percentile: Top 75%
Mycobacterium research and diagnosis
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Case Report of a Non-Small-Cell Lung Cancer Patient with Cytotoxic Chemotherapy-Induced Neutropenia Treated with Korean Medicine — Don-Hyun Choi, Min-Seob Lee, et al. · The Journal of Internal Korean Medicine (2025) | TGRS Research Map | TGRS