Систематический обзор хирургии клапанов сердца с непрерывной коронарной перфузией на работающем сердце у пациентов с низкой фракцией выброса левого желудочка.
Aim. Beating-heart continuous coronary perfusion (BHCCP) is an alternative to cardioplegic arrest in valve surgery, potentially reducing ischemic reperfusion injury, especially in high-risk patients with low left ventricular ejection fraction (LVEF). Materials and methods. A systematic review of prospective and observational studies was conducted, focusing on BHCCP versus cardioplegia in valve surgery, with emphasis on patients with LVEF <35%. Results. Studies (e.g., Matsumoto et al., 2002) showed no significant difference in mortality or major complications, but BHCCP reduced myocardial damage markers (e.g., Troponin I, CK-MB) by 20–40% compared to cardioplegia. Clinical outcomes remained comparable across groups. Conclusion. BHCCP is a safe alternative to cardioplegia, with potential benefits in myocardial protection, though high-quality randomized trials are needed to confirm clinical superiority.
Authors
- Г Муллабаева (ORCID: https://orcid.org/0000-0003-3255-2443)
- И Шарипов (ORCID: https://orcid.org/0009-0007-3202-8939)
- У Хайруллаев
Publication Details
- Journal
- Cardiology of Uzbekistan.
- Published
- 2025-06-30
- DOI
- https://doi.org/10.70626/cardiouz-2025-2-00046
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00