Систематический обзор хирургии клапанов сердца с непрерывной коронарной перфузией на работающем сердце у пациентов с низкой фракцией выброса левого желудочка.

Aim. Beating-heart continuous coronary perfusion (BHCCP) is an alternative to cardioplegic arrest in valve surgery, potentially reducing ischemic reperfusion injury, especially in high-risk patients with low left ventricular ejection fraction (LVEF). Materials and methods. A systematic review of prospective and observational studies was conducted, focusing on BHCCP versus cardioplegia in valve surgery, with emphasis on patients with LVEF <35%. Results. Studies (e.g., Matsumoto et al., 2002) showed no significant difference in mortality or major complications, but BHCCP reduced myocardial damage markers (e.g., Troponin I, CK-MB) by 20–40% compared to cardioplegia. Clinical outcomes remained comparable across groups. Conclusion. BHCCP is a safe alternative to cardioplegia, with potential benefits in myocardial protection, though high-quality randomized trials are needed to confirm clinical superiority.

Authors

Publication Details

Journal
Cardiology of Uzbekistan.
Published
2025-06-30
DOI
https://doi.org/10.70626/cardiouz-2025-2-00046
Primary Topic
Cardiac Ischemia and Reperfusion
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Систематический обзор хирургии клапанов сердца с непрерывной коронарной перфузией на работающем сердце у пациентов с низкой фракцией выброса левого желудочка.

Г Муллабаева, И Шарипов, У Хайруллаев
Cardiology of Uzbekistan.
Cardiac Ischemia and Reperfusion
article

Систематический обзор хирургии клапанов сердца с непрерывной коронарной перфузией на работающем сердце у пациентов с низкой фракцией выброса левого желудочка.

Г Муллабаева, И Шарипов, У Хайруллаев
article en

Abstract

Aim. Beating-heart continuous coronary perfusion (BHCCP) is an alternative to cardioplegic arrest in valve surgery, potentially reducing ischemic reperfusion injury, especially in high-risk patients with low left ventricular ejection fraction (LVEF). Materials and methods. A systematic review of prospective and observational studies was conducted, focusing on BHCCP versus cardioplegia in valve surgery, with emphasis on patients with LVEF <35%. Results. Studies (e.g., Matsumoto et al., 2002) showed no significant difference in mortality or major complications, but BHCCP reduced myocardial damage markers (e.g., Troponin I, CK-MB) by 20–40% compared to cardioplegia. Clinical outcomes remained comparable across groups. Conclusion. BHCCP is a safe alternative to cardioplegia, with potential benefits in myocardial protection, though high-quality randomized trials are needed to confirm clinical superiority.

Cardiology of Uzbekistan.Vol. 2(2)
Openalex Percentile: Top 74%
Cardiac Ischemia and Reperfusion
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.