A Real-World Clinical Evaluation of Ganciclovir Exposure and Cytomegalovirus Viremia Outcomes After Adult Kidney Transplantation

In the early phase after kidney transplantation, exposure to GCV is highly variable among patients and underexposure to GCV occurs frequently. However, DGF was not associated with reduced exposure to GCV or CMV viremia, nor was early exposure to GCV correlated with CMV outcomes or leukopenia.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-07-21
DOI
https://doi.org/10.1097/ftd.0000000000001363
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

A Real-World Clinical Evaluation of Ganciclovir Exposure and Cytomegalovirus Viremia Outcomes After Adult Kidney Transplantation

Dennis A. Hesselink, Brenda C. M. de Winter, Lukas K. van Vugt, Rawan Saleh
Therapeutic Drug Monitoring
Cytomegalovirus and herpesvirus research
article

A Real-World Clinical Evaluation of Ganciclovir Exposure and Cytomegalovirus Viremia Outcomes After Adult Kidney Transplantation

Dennis A. Hesselink, Brenda C. M. de Winter, Lukas K. van Vugt, Rawan Saleh
article en

Abstract

In the early phase after kidney transplantation, exposure to GCV is highly variable among patients and underexposure to GCV occurs frequently. However, DGF was not associated with reduced exposure to GCV or CMV viremia, nor was early exposure to GCV correlated with CMV outcomes or leukopenia.

Therapeutic Drug MonitoringVol. 48(1)
Erasmus MC (NL), Erasmus MC Cancer Institute (NL), Erasmus University Rotterdam (NL)
Openalex Percentile: Top 75%
Cytomegalovirus and herpesvirus research
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A Real-World Clinical Evaluation of Ganciclovir Exposure and Cytomegalovirus Viremia Outcomes After Adult Kidney Transplantation — Dennis A. Hesselink, Brenda C. M. de Winter, et al. · Therapeutic Drug Monitoring (2025) | TGRS Research Map | TGRS