Chokehold with ‘rear naked choke’ and delayed post-hypoxic leukoencephalopathy: a new form of assault in Mexico City
In Mexico City, a 49-year-old man underwent strangulation, which led to hypoxic-ischemic encephalopathy (HIE) and subsequently to delayed post-hypoxic leukoencephalopathy (DPHL), a rare demyelinating condition. Following the attack, he exhibited aphasia, dysphagia, and other neuropsychiatric symptoms that progressed to dementia. Imaging and brain biopsy analyses disclosed extensive ischemic damage and reactive gliosis. This case underscores the link between strangulation, acute HIE, and the subsequent development of DPHL, as well as an interpretation of the physiological implications of DPHL due to strangulation.
Authors
- Karla Aketzalli Hernández-Contreras (ORCID: https://orcid.org/0000-0003-3677-4692)
- Carlos Castillo-Rangel (ORCID: https://orcid.org/0000-0003-2956-5112)
- Cristofer Zarate-Calderon (ORCID: https://orcid.org/0000-0002-6039-3745)
- Gerardo Marín (ORCID: https://orcid.org/0000-0003-4782-5504)
- Carlos Castillo-Soriano
Institutions
- Cleveland Clinic (US)
- Universidad Veracruzana (MX)
- Institute for Social Security and Services for State Workers (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1007/s00701-025-06601-9
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.00