Chokehold with ‘rear naked choke’ and delayed post-hypoxic leukoencephalopathy: a new form of assault in Mexico City

In Mexico City, a 49-year-old man underwent strangulation, which led to hypoxic-ischemic encephalopathy (HIE) and subsequently to delayed post-hypoxic leukoencephalopathy (DPHL), a rare demyelinating condition. Following the attack, he exhibited aphasia, dysphagia, and other neuropsychiatric symptoms that progressed to dementia. Imaging and brain biopsy analyses disclosed extensive ischemic damage and reactive gliosis. This case underscores the link between strangulation, acute HIE, and the subsequent development of DPHL, as well as an interpretation of the physiological implications of DPHL due to strangulation.

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Publication Details

Journal
Acta Neurochirurgica
Published
2025-07-19
DOI
https://doi.org/10.1007/s00701-025-06601-9
Primary Topic
Heme Oxygenase-1 and Carbon Monoxide
Type
article
Field-Weighted Citation Impact
0.00
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article

Chokehold with ‘rear naked choke’ and delayed post-hypoxic leukoencephalopathy: a new form of assault in Mexico City

Karla Aketzalli Hernández-Contreras, Carlos Castillo-Rangel, Cristofer Zarate-Calderon, Gerardo Marín et al.
Acta Neurochirurgica
Heme Oxygenase-1 and Carbon Monoxide
article

Chokehold with ‘rear naked choke’ and delayed post-hypoxic leukoencephalopathy: a new form of assault in Mexico City

Karla Aketzalli Hernández-Contreras, Carlos Castillo-Rangel, Cristofer Zarate-Calderon, Gerardo Marín, Carlos Castillo-Soriano
article en

Abstract

In Mexico City, a 49-year-old man underwent strangulation, which led to hypoxic-ischemic encephalopathy (HIE) and subsequently to delayed post-hypoxic leukoencephalopathy (DPHL), a rare demyelinating condition. Following the attack, he exhibited aphasia, dysphagia, and other neuropsychiatric symptoms that progressed to dementia. Imaging and brain biopsy analyses disclosed extensive ischemic damage and reactive gliosis. This case underscores the link between strangulation, acute HIE, and the subsequent development of DPHL, as well as an interpretation of the physiological implications of DPHL due to strangulation.

Acta NeurochirurgicaVol. 167(1)
Cleveland Clinic (US), Universidad Veracruzana (MX), Institute for Social Security and Services for State Workers (MX), Tecnológico de Monterrey (MX)
Openalex Percentile: Top 84%
Heme Oxygenase-1 and Carbon Monoxide
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