Laboratory Practices for the Detection and Characterization of Cryoglobulins and Cryofibrinogen

CGs testing has long been common in laboratories, and the analytical and pre-analytical procedures are well known, in contrast to CF testing, which has only emerged in recent years. Therefore, appropriate procedures are needed for testing both cryoproteins to optimize economic and human resources and reduce laboratory diagnostic times. At last, confirming a clinical suspicion of cryoproteinemia in a short time could improve patient outcomes, allowing suitable therapies to be implemented for vasculitis and related thromboembolic phenomena.