The Impact of Synergistic Therapy Between Colistin and Meropenem on Outcomes of People With Pneumonia or Bloodstream Infection Due to Carbapenem-Resistant Gram-Negative Pathogens
Colistin-based, synergistic combination treatment with meropenem (compared to nonsynergistic colistin-based therapy) was associated with decreased clinical failure, particularly in people with pneumonia and A. baumannii.
Authors
- Matthew Sims (ORCID: https://orcid.org/0000-0002-4427-6653)
- Laura Susick (ORCID: https://orcid.org/0000-0002-1389-837X)
- Dora Tancheva
- Keith S. Kaye (ORCID: https://orcid.org/0000-0003-2051-1732)
- Sotirios Tsiodras (ORCID: https://orcid.org/0000-0002-0463-4321)
- Yehuda Carmeli
- David P. Calfee (ORCID: https://orcid.org/0000-0002-4647-790X)
- Hamadullah Shaikh
- Katie Latack
- Varduhi Ghazyaran
- L. Power (ORCID: https://orcid.org/0000-0002-9069-512X)
- Sorabh Dhar (ORCID: https://orcid.org/0000-0002-1497-7643)
- George L. Daikos (ORCID: https://orcid.org/0000-0001-5365-4874)
- Emmanuel Roilides (ORCID: https://orcid.org/0000-0002-0202-364X)
- Dror Marchaim (ORCID: https://orcid.org/0009-0003-6745-4939)
- Emanuele Durante‐Mangoni (ORCID: https://orcid.org/0000-0002-5381-3537)
- L. Leibovici
- Kyle Stamper
- Achilleas Gikas (ORCID: https://orcid.org/0000-0002-8455-9631)
- Cheng‐Hsun Chiu (ORCID: https://orcid.org/0000-0003-4324-7743)
- Αναστασία Κοτανίδου (ORCID: https://orcid.org/0000-0003-4703-0082)
- Christine C. Chiou
- Jacinda C. Abdul‐Mutakabbir (ORCID: https://orcid.org/0000-0003-4162-6408)
- Mical Paul (ORCID: https://orcid.org/0000-0003-2317-1112)
- Gopi Patel (ORCID: https://orcid.org/0000-0003-1877-5608)
- George Divine (ORCID: https://orcid.org/0000-0002-8465-0523)
- Visanu Thamlikitkul (ORCID: https://orcid.org/0000-0002-0044-5988)
- Michael Samarkos (ORCID: https://orcid.org/0000-0001-9630-9712)
- Jason M. Pogue (ORCID: https://orcid.org/0000-0003-4780-6215)
- L. Silvia Muñoz-Price (ORCID: https://orcid.org/0000-0001-8654-5746)
- Daniel H. Kett
- Michael Joseph Rybak (ORCID: https://orcid.org/0000-0003-2220-0081)
- Mariya Huralska
Institutions
- Eugene Applebaum College of Pharmacy and Health Sciences (US)
- National Institutes of Health (US)
- Siriraj Hospital (TH)
- Henry Ford Health System (US)
- Chang Gung University (TW)
- Wayne State University (US)
- American Association of Colleges of Pharmacy (US)
- National and Kapodistrian University of Athens (GR)
- Cornell University (US)
- Aristotle University of Thessaloniki (GR)
- Mahidol University (TH)
- University of Michigan (US)
- Detroit Medical Center (US)
- Rabin Medical Center (IL)
- Rambam Health Care Campus (IL)
- Johnson University (US)
- Jackson Memorial Hospital (US)
- Emerald Coast Science Center (US)
- University of Michigan–Flint (US)
- National Institute of Emergency Medicine "Pirogov" (BG)
- Mount Sinai Hospital (US)
- Spine Institute on the Emerald Coast (US)
- Assaf Harofeh Medical Center (IL)
- Michigan Medicine (US)
- Laiko General Hospital of Athens (GR)
- Infectious Diseases Institute (UG)
- Ippokrateio General Hospital of Thessaloniki (GR)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
- CNR de la Résistance aux Antibiotiques (FR)
- National Institute of Allergy and Infectious Diseases (US)
- University Hospital of Heraklion (GR)
- University General Hospital Attikon (GR)
- Ospedale Monaldi (IT)
- Chiayi Chang Gung Memorial Hospital (TW)
- Beaumont Hospital, Troy (US)
- Hippocration General Hospital (GR)
- University of Montana (US)
- Athens State University (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1093/cid/ciaf398
- Citations
- 5
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 6.31