The Impact of Synergistic Therapy Between Colistin and Meropenem on Outcomes of People With Pneumonia or Bloodstream Infection Due to Carbapenem-Resistant Gram-Negative Pathogens

Colistin-based, synergistic combination treatment with meropenem (compared to nonsynergistic colistin-based therapy) was associated with decreased clinical failure, particularly in people with pneumonia and A. baumannii.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2025-07-19
DOI
https://doi.org/10.1093/cid/ciaf398
Citations
5
Primary Topic
Antibiotic Use and Resistance
Type
article
Field-Weighted Citation Impact
6.31
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article

The Impact of Synergistic Therapy Between Colistin and Meropenem on Outcomes of People With Pneumonia or Bloodstream Infection Due to Carbapenem-Resistant Gram-Negative Pathogens

Matthew Sims, Laura Susick, Dora Tancheva, Keith S. Kaye et al.
5 citations
Clinical Infectious Diseases
Antibiotic Use and Resistance
6.31
article

The Impact of Synergistic Therapy Between Colistin and Meropenem on Outcomes of People With Pneumonia or Bloodstream Infection Due to Carbapenem-Resistant Gram-Negative Pathogens

Matthew Sims, Laura Susick, Dora Tancheva, Keith S. Kaye, Sotirios Tsiodras, Yehuda Carmeli, David P. Calfee, Hamadullah Shaikh, Katie Latack, Varduhi Ghazyaran, L. Power, Sorabh Dhar, George L. Daikos, Emmanuel Roilides, Dror Marchaim, Emanuele Durante‐Mangoni, L. Leibovici, Kyle Stamper, Achilleas Gikas, Cheng‐Hsun Chiu, Αναστασία Κοτανίδου, Christine C. Chiou, Jacinda C. Abdul‐Mutakabbir, Mical Paul, Gopi Patel, George Divine, Visanu Thamlikitkul, Michael Samarkos, Jason M. Pogue, L. Silvia Muñoz-Price, Daniel H. Kett, Michael Joseph Rybak, Mariya Huralska
article en
5 citations

Abstract

Colistin-based, synergistic combination treatment with meropenem (compared to nonsynergistic colistin-based therapy) was associated with decreased clinical failure, particularly in people with pneumonia and A. baumannii.

Clinical Infectious DiseasesVol. 82(3)
Eugene Applebaum College of Pharmacy and Health Sciences (US), National Institutes of Health (US), Siriraj Hospital (TH), Henry Ford Health System (US), Chang Gung University (TW), Wayne State University (US), American Association of Colleges of Pharmacy (US), National and Kapodistrian University of Athens (GR), Cornell University (US), Aristotle University of Thessaloniki (GR), Mahidol University (TH), University of Michigan (US), Detroit Medical Center (US), Rabin Medical Center (IL), Rambam Health Care Campus (IL), Johnson University (US), Jackson Memorial Hospital (US), Emerald Coast Science Center (US), University of Michigan–Flint (US), National Institute of Emergency Medicine "Pirogov" (BG), Mount Sinai Hospital (US), Spine Institute on the Emerald Coast (US), Assaf Harofeh Medical Center (IL), Michigan Medicine (US), Laiko General Hospital of Athens (GR), Infectious Diseases Institute (UG), Ippokrateio General Hospital of Thessaloniki (GR), Mahidol Oxford Tropical Medicine Research Unit (TH), CNR de la Résistance aux Antibiotiques (FR), National Institute of Allergy and Infectious Diseases (US), University Hospital of Heraklion (GR), University General Hospital Attikon (GR), Ospedale Monaldi (IT), Chiayi Chang Gung Memorial Hospital (TW), Beaumont Hospital, Troy (US), Hippocration General Hospital (GR), University of Montana (US), Athens State University (US)
Good health and well-being
Openalex Percentile: Top 3%
Antibiotic Use and Resistance
6.31
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