Comparison of two preprocessing methods for 18F-Flortaucipir PET quantification in Alzheimer’s disease
While preprocessing in native and standard space is adequate for quantifying <sup>18</sup>F-Flortaucipir PET and for discriminating AD patients, higher accuracy can be obtained in the mesial temporal regions and to predict cognitive decline using processing in native space.
Authors
- Nicholas James Ashton (ORCID: https://orcid.org/0000-0002-3579-8804)
- Cecilia Boccalini (ORCID: https://orcid.org/0000-0002-3518-436X)
- Kaj Blennow (ORCID: https://orcid.org/0000-0002-1890-4193)
- Max Scheffler
- Valentina Garibotto (ORCID: https://orcid.org/0000-0003-2422-698X)
- Ruben Smith (ORCID: https://orcid.org/0000-0001-7147-0112)
- Giovanni Battista Frisoni (ORCID: https://orcid.org/0000-0001-7075-7082)
- Débora Elisa Peretti (ORCID: https://orcid.org/0000-0002-3033-8817)
- Henrik Zetterberg (ORCID: https://orcid.org/0000-0002-4671-6763)
- Elif Harput
Institutions
- University of Geneva (CH)
- University of Science and Technology of China (CN)
- University of Wisconsin–Madison (US)
- University of Arizona (US)
- Lund University (SE)
- Stavanger University Hospital (NO)
- Sahlgrenska University Hospital (SE)
- Sorbonne Université (FR)
- University Hospital of Geneva (CH)
- Institut de Myologie (FR)
- Pitié-Salpêtrière Hospital (FR)
- UK Dementia Research Institute (GB)
- Centre d'Imagerie BioMedicale (CH)
- Skåne University Hospital (SE)
- Banner Sun Health Research Institute (US)
- National Hospital for Neurology and Neurosurgery (GB)
- Institut du Cerveau (FR)
- University College London (GB)
- Geneva College (US)
- University of Gothenburg (SE)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1007/s00259-025-07452-3
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Eidgenössische Technische Hochschule Zürich
- Université de Genève
- Avid Radiopharmaceuticals