Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway
PVT1 level was significantly elevated in luminal and basal-like BC subtypes. Knockdown of PVT1 could inhibit cell proliferation of these two BC subtypes partly through activating LATS2/Hippo signaling pathway.
Authors
- Haibo Zhang (ORCID: https://orcid.org/0000-0001-5965-5069)
- Ying Zeng (ORCID: https://orcid.org/0000-0003-2795-4616)
- Guo Wang (ORCID: https://orcid.org/0000-0002-8359-9076)
Institutions
- Central South University (CN)
- Changsha Medical University (CN)
- Hangzhou Women’s Hospital (CN)
- Xiangya Hospital Central South University (CN)
- University of South China (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-07-19
- DOI
- https://doi.org/10.1186/s12957-025-03944-6
- Citations
- 1
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Natural Science Foundation of China