Potential auxiliary diagnostic role of pentraxin 3 in plasma and bronchoalveolar lavage fluid for pulmonary tuberculosis

Plasma PTX3 levels have limited diagnostic utility in distinguishing tuberculosis from other pulmonary conditions, whereas BALF PTX3 levels exhibit more possible auxiliary diagnosis ability as an auxiliary diagnostic indicator, offering a localized assessment of lung inflammation. BALF PTX3 could be a helpful adjunct in diagnosing TB, particularly in cases where conventional sputum-based tests are inconclusive. Further research is needed to validate these findings.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2025-07-19
DOI
https://doi.org/10.1186/s13019-025-03544-1
Primary Topic
Biomarkers in Disease Mechanisms
Type
article
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article

Potential auxiliary diagnostic role of pentraxin 3 in plasma and bronchoalveolar lavage fluid for pulmonary tuberculosis

Xiufeng Huang, Lu Liu, Yu Zhang, Hongxing Li
Journal of Cardiothoracic Surgery
Biomarkers in Disease Mechanisms
article

Potential auxiliary diagnostic role of pentraxin 3 in plasma and bronchoalveolar lavage fluid for pulmonary tuberculosis

Xiufeng Huang, Lu Liu, Yu Zhang, Hongxing Li
article en

Abstract

Plasma PTX3 levels have limited diagnostic utility in distinguishing tuberculosis from other pulmonary conditions, whereas BALF PTX3 levels exhibit more possible auxiliary diagnosis ability as an auxiliary diagnostic indicator, offering a localized assessment of lung inflammation. BALF PTX3 could be a helpful adjunct in diagnosing TB, particularly in cases where conventional sputum-based tests are inconclusive. Further research is needed to validate these findings.

Journal of Cardiothoracic SurgeryVol. 20(1)
Soochow University (CN), Wuxi Ninth People's Hospital (CN), Taizhou First People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 81%
Biomarkers in Disease Mechanisms
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Potential auxiliary diagnostic role of pentraxin 3 in plasma and bronchoalveolar lavage fluid for pulmonary tuberculosis — Xiufeng Huang, Lu Liu, et al. · Journal of Cardiothoracic Surgery (2025) | TGRS Research Map | TGRS